用于调节生物参数的新型优化分数阶系统

IF 1.6 4区 工程技术 Q3 ENGINEERING, ELECTRICAL & ELECTRONIC
Tapaswini Sahu, Madhab Chandra Tripathy, Ranjan Kumar Jena
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引用次数: 0

摘要

在当代生物学研究和应用中,控制系统已成为了解和管理人类生物系统复杂动态不可或缺的因素。鉴于胰腺结构、蛋白质形成、胰岛素和葡萄糖调节以及遗传调控网络(GRN)等组件的关键作用,这些系统中的任何干扰都可能导致严重的健康问题。为了克服这些问题,我们引入了一种新型混合控制器,称为基于模糊狮子的优化分数阶系统(FL-OFOS),用于评估系统的性能。该控制器旨在有效控制和调节人体生物系统的关键组成部分,包括胰岛素动态、蛋白质合成、胰腺功能和 GRN 管理。该控制器专门用于调节人体生物系统中的胰岛素、蛋白质合成、胰腺功能和 GRN 动态。通过加入模糊狮子函数,实现了生物参数值的优化。这项研究的结果凸显了 FL-OFOS 控制器在优化和调节各种生物参数方面的功效。该系统具有误差率小、响应时间快、过冲小、控制精度和准确度高等特点。所提出的控制器误差率最小,仅为 0.98%,结果仅出现轻微的过冲。因此,FL-OFOS 控制器可在生物系统领域带来巨大收益和最佳结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A novel optimized fractional order system for tuning biological parameters

In contemporary biological research and applications, control systems have become indispensable for understanding and managing the intricate dynamics of the human biological system. Given the critical role of components such as the pancreas structure, protein formation, insulin and glucose regulation, and the genetic regulatory network (GRN), any disturbances in these systems can lead to severe health issues. To overcome these issues, to introduced a novel hybrid controller called the fuzzy lion-based optimized fractional order system (FL-OFOS) for evaluating the performance of the system. This controller aims to efficiently govern and regulate key components of the human biological system, including insulin dynamics, protein synthesis, pancreas functionality, and GRN management. The controller is specifically tailored to regulate insulin, protein synthesis, pancreas function, and GRN dynamics within the human biological system. The optimization of biological parameter values is achieved through the incorporation of the fuzzy lion function. The results of this study highlight the efficacy of the FL-OFOS controller in optimizing and regulating various biological parameters. The system demonstrates minimal error rates, rapid response times, reduced overshoot, and high control precision and accuracy. The proposed controller achieves a minimal error rate of 0.98%, with only minor overshoot occurring in the outcomes. As a result, the FL-OFOS controller offers substantial gains and delivers optimal results in the realm of biological systems.

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来源期刊
CiteScore
4.60
自引率
6.20%
发文量
101
审稿时长
>12 weeks
期刊介绍: Prediction through modelling forms the basis of engineering design. The computational power at the fingertips of the professional engineer is increasing enormously and techniques for computer simulation are changing rapidly. Engineers need models which relate to their design area and which are adaptable to new design concepts. They also need efficient and friendly ways of presenting, viewing and transmitting the data associated with their models. The International Journal of Numerical Modelling: Electronic Networks, Devices and Fields provides a communication vehicle for numerical modelling methods and data preparation methods associated with electrical and electronic circuits and fields. It concentrates on numerical modelling rather than abstract numerical mathematics. Contributions on numerical modelling will cover the entire subject of electrical and electronic engineering. They will range from electrical distribution networks to integrated circuits on VLSI design, and from static electric and magnetic fields through microwaves to optical design. They will also include the use of electrical networks as a modelling medium.
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