增强抗肿瘤治疗的纳米药物温和光热疗法策略

IF 4 Q2 ENGINEERING, BIOMEDICAL

Advanced Nanobiomed Research Pub Date : 2024-03-07 DOI:10.1002/anbr.202470031

Yongjuan Li, Xinran Zhu, Ya Dong, Yang Yang, Danyang Shen, Zhenzhen Li, Rui Li, Xiaowei Dang, Zhihai Qin, Kelong Fan

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引用次数: 0

摘要

光热疗法轻度光热疗法（mPTT，45 °C）在抗肿瘤治疗中备受关注，尽管热休克蛋白会引起热阻。在第 2300094 号文章中，Kelong Fan 及其合作者讨论了光热疗法的现状，阐明了温和光热疗法的基本机制，强调了温和光热疗法在联合治疗中的优势，并探讨了纳米药物提高温和光热疗法疗效的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Nanomedicine-Enabled Mild Photothermal Therapy Strategies for Enhanced Antitumor Treatment

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Nanomedicine-Enabled Mild Photothermal Therapy Strategies for Enhanced Antitumor Treatment

Photothermal Therapy

Mild photothermal therapy (mPTT, <45 °C) has garnered considerable attention in antitumor therapy, despite the thermal resistance induced by heat shock proteins. In article 2300094, Kelong Fan and co-workers discuss the current landscape of photothermal agents, elucidate the underlying mechanisms of mPTT, highlight the benefits of mPTT in combination therapy, and explore the potential of nanomedicines to enhance mPTT efficacy.

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来源期刊

Advanced Nanobiomed Research nanomedicine, bioengineering and biomaterials-

CiteScore

5.00

自引率

5.90%

发文量

审稿时长

21 weeks

期刊介绍： Advanced NanoBiomed Research will provide an Open Access home for cutting-edge nanomedicine, bioengineering and biomaterials research aimed at improving human health. The journal will capture a broad spectrum of research from increasingly multi- and interdisciplinary fields of the traditional areas of biomedicine, bioengineering and health-related materials science as well as precision and personalized medicine, drug delivery, and artificial intelligence-driven health science. The scope of Advanced NanoBiomed Research will cover the following key subject areas: ▪ Nanomedicine and nanotechnology, with applications in drug and gene delivery, diagnostics, theranostics, photothermal and photodynamic therapy and multimodal imaging. ▪ Biomaterials, including hydrogels, 2D materials, biopolymers, composites, biodegradable materials, biohybrids and biomimetics (such as artificial cells, exosomes and extracellular vesicles), as well as all organic and inorganic materials for biomedical applications. ▪ Biointerfaces, such as anti-microbial surfaces and coatings, as well as interfaces for cellular engineering, immunoengineering and 3D cell culture. ▪ Biofabrication including (bio)inks and technologies, towards generation of functional tissues and organs. ▪ Tissue engineering and regenerative medicine, including scaffolds and scaffold-free approaches, for bone, ligament, muscle, skin, neural, cardiac tissue engineering and tissue vascularization. ▪ Devices for healthcare applications, disease modelling and treatment, such as diagnostics, lab-on-a-chip, organs-on-a-chip, bioMEMS, bioelectronics, wearables, actuators, soft robotics, and intelligent drug delivery systems. with a strong focus on applications of these fields, from bench-to-bedside, for treatment of all diseases and disorders, such as infectious, autoimmune, cardiovascular and metabolic diseases, neurological disorders and cancer; including pharmacology and toxicology studies.