红树莓对癌症的预防和抑制作用

IF 1.5 4区农林科学 Q3 PLANT SCIENCES

Journal of Berry Research Pub Date : 2024-03-04 DOI:10.3233/jbr-240004

Zexiu Qi, Bei Yang, Francesca Giampieri, Danila Cianciosi, José Miguel Alvarez-Suarez, Maria Elexpuru-Zabaleta, Josè L. Quiles, Tamara Y. Forbes-Hernandez, Di Zhang, Weibin Bai, Lingmin Tian, Bruno Mezzetti, Maurizio Battino, Yasmany Armas Diaz

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引用次数: 0

摘要

红树莓因其营养和生物活性成分以及抗肿瘤等潜在健康功效而越来越受到人们的关注。本综述旨在描述红树莓的抗氧化活性，强调花青素和鞣花丹宁是红树莓多酚中的主要成分；它还概述了红树莓与其通过调节氧化应激抑制癌细胞生长的作用之间的联系。大量研究表明，红树莓能够通过抑制增殖、迁移和自噬，以及调节细胞周期、血管生成和 DNA 损伤修复来阻止癌细胞的发展。本综述揭示了越来越多的证据支持抗氧化剂是水果消费与癌症预防之间的重要环节。

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The preventive and inhibitory effects of red raspberries on cancer

Red raspberries are gaining attention more and more for their nutritional and bioactive components, with potential health effects such as antitumor properties. This review aims to describe the antioxidant activities of red raspberries, emphasizing the role of anthocyanins and ellagitannins as primary contributors among red raspberry polyphenols; it also outlined the connection between red raspberries and their role in inhibiting cancer cell growth by regulating oxidative stress. Numerous studies suggest that red raspberries are able to block cancer cell progression by inhibiting proliferation, migration, and autophagy, as well as regulating the cell cycle, angiogenesis, and DNA damage repair. This review sheds light to the growing evidence supporting antioxidants as a crucial link between fruit consumption and cancer prevention.

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来源期刊

Journal of Berry Research Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

3.50

自引率

11.80%

发文量

期刊介绍： The main objective of the Journal of Berry Research is to improve the knowledge about quality and production of berries to benefit health of the consumers and maintain profitable production using sustainable systems. The objective will be achieved by focusing on four main areas of research and development: From genetics to variety evaluation Nursery production systems and plant quality control Plant physiology, biochemistry and molecular biology, as well as cultural management Health for the consumer: components and factors affecting berries'' nutritional value Specifically, the journal will cover berries (strawberry, raspberry, blackberry, blueberry, cranberry currants, etc.), as well as grapes and small soft fruit in general (e.g., kiwi fruit). It will publish research results covering all areas of plant breeding, including plant genetics, genomics, functional genomics, proteomics and metabolomics, plant physiology, plant pathology and plant development, as well as results dealing with the chemistry and biochemistry of bioactive compounds contained in such fruits and their possible role in human health. Contributions detailing possible pharmacological, medical or therapeutic use or dietary significance will be welcomed in addition to studies regarding biosafety issues of genetically modified plants.