David Jordan, John Elfar, Chian K Kwoh, Zong-Ming Li
{"title":"通过计算机断层扫描验证估算斜方肌掌关节的影像关节间隙。","authors":"David Jordan, John Elfar, Chian K Kwoh, Zong-Ming Li","doi":"10.1117/1.JMI.11.2.024001","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>Joint space width (JSW) is a common metric used to evaluate joint structure on plain radiographs. For the hand, quantitative techniques are available for evaluation of the JSW of finger joints; however, such techniques have been difficult to establish for the trapeziometacarpal (TMC) joint. This study aimed to develop a validated method for measuring the radiographic joint space of the healthy TMC joint.</p><p><strong>Approach: </strong>Computed tomographic scans were taken of 15 cadaveric hands. The location of a JSW analysis region on the articular surface of the first metacarpal was established in 3D space and standardized in a 2D projection. The standardized region was applied to simulated radiographic images. A correction factor was defined as the ratio of the CT-based and radiograph-based joint space measurements. Leave-one-out validation was used to correct the radiograph-based measurements. A t-test was used to evaluate the difference between CT-based and corrected radiograph-based measurements (<math><mrow><mi>α</mi><mo>=</mo><mn>0.05</mn></mrow></math>).</p><p><strong>Results: </strong>The CT-based and radiograph-based measurements of JSW were <math><mrow><mn>3.61</mn><mo>±</mo><mn>0.72</mn><mtext> </mtext><mi>mm</mi></mrow></math> and <math><mrow><mn>2.18</mn><mo>±</mo><mn>0.40</mn><mtext> </mtext><mi>mm</mi></mrow></math>, respectively. The correction factor for radiograph-based joint space was <math><mrow><mn>1.69</mn><mo>±</mo><mn>0.41</mn></mrow></math>. Before correction, the difference between the CT-based and radiograph-based joint space was 1.43 mm [95% CI: <math><mrow><mn>0.99</mn><mo>-</mo><mn>1.86</mn><mtext> </mtext><mi>mm</mi></mrow></math>; <math><mrow><mi>p</mi><mo><</mo><mn>0.001</mn></mrow></math>]. After correction, the difference was <math><mrow><mo>-</mo><mn>0.11</mn><mtext> </mtext><mi>mm</mi></mrow></math> [95% CI: <math><mrow><mo>-</mo><mn>0.63</mn><mo>-</mo><mn>0.41</mn><mtext> </mtext><mi>mm</mi></mrow></math>; <math><mrow><mi>p</mi><mo>=</mo><mn>0.669</mn></mrow></math>].</p><p><strong>Conclusions: </strong>Corrected measurements of radiographic TMC JSW agreed well with CT-measured JSW. With <i>in-vivo</i> validation, the developed methodology has potential for automated and accurate radiographic measurement of TMC JSW.</p>","PeriodicalId":47707,"journal":{"name":"Journal of Medical Imaging","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911767/pdf/","citationCount":"0","resultStr":"{\"title\":\"Estimation of radiographic joint space of the trapeziometacarpal joint with computed tomographic validation.\",\"authors\":\"David Jordan, John Elfar, Chian K Kwoh, Zong-Ming Li\",\"doi\":\"10.1117/1.JMI.11.2.024001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>Joint space width (JSW) is a common metric used to evaluate joint structure on plain radiographs. For the hand, quantitative techniques are available for evaluation of the JSW of finger joints; however, such techniques have been difficult to establish for the trapeziometacarpal (TMC) joint. This study aimed to develop a validated method for measuring the radiographic joint space of the healthy TMC joint.</p><p><strong>Approach: </strong>Computed tomographic scans were taken of 15 cadaveric hands. The location of a JSW analysis region on the articular surface of the first metacarpal was established in 3D space and standardized in a 2D projection. The standardized region was applied to simulated radiographic images. A correction factor was defined as the ratio of the CT-based and radiograph-based joint space measurements. Leave-one-out validation was used to correct the radiograph-based measurements. A t-test was used to evaluate the difference between CT-based and corrected radiograph-based measurements (<math><mrow><mi>α</mi><mo>=</mo><mn>0.05</mn></mrow></math>).</p><p><strong>Results: </strong>The CT-based and radiograph-based measurements of JSW were <math><mrow><mn>3.61</mn><mo>±</mo><mn>0.72</mn><mtext> </mtext><mi>mm</mi></mrow></math> and <math><mrow><mn>2.18</mn><mo>±</mo><mn>0.40</mn><mtext> </mtext><mi>mm</mi></mrow></math>, respectively. The correction factor for radiograph-based joint space was <math><mrow><mn>1.69</mn><mo>±</mo><mn>0.41</mn></mrow></math>. Before correction, the difference between the CT-based and radiograph-based joint space was 1.43 mm [95% CI: <math><mrow><mn>0.99</mn><mo>-</mo><mn>1.86</mn><mtext> </mtext><mi>mm</mi></mrow></math>; <math><mrow><mi>p</mi><mo><</mo><mn>0.001</mn></mrow></math>]. After correction, the difference was <math><mrow><mo>-</mo><mn>0.11</mn><mtext> </mtext><mi>mm</mi></mrow></math> [95% CI: <math><mrow><mo>-</mo><mn>0.63</mn><mo>-</mo><mn>0.41</mn><mtext> </mtext><mi>mm</mi></mrow></math>; <math><mrow><mi>p</mi><mo>=</mo><mn>0.669</mn></mrow></math>].</p><p><strong>Conclusions: </strong>Corrected measurements of radiographic TMC JSW agreed well with CT-measured JSW. With <i>in-vivo</i> validation, the developed methodology has potential for automated and accurate radiographic measurement of TMC JSW.</p>\",\"PeriodicalId\":47707,\"journal\":{\"name\":\"Journal of Medical Imaging\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10911767/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1117/1.JMI.11.2.024001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/3/4 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Imaging","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1117/1.JMI.11.2.024001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/3/4 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
目的:关节间隙宽度(JSW)是在X光平片上评估关节结构的常用指标。就手部而言,有定量技术可用于评估手指关节的关节间隙宽度;然而,这种技术却很难用于梯形掌(TMC)关节。本研究旨在开发一种有效的方法,用于测量健康 TMC 关节的放射学关节间隙:方法:对 15 只尸体手部进行计算机断层扫描。在三维空间中确定第一掌骨关节面上 JSW 分析区域的位置,并在二维投影中将其标准化。标准化区域应用于模拟放射影像。校正因子被定义为基于 CT 和基于射线照相的关节空间测量值之比。采用留空验证来校正基于射线照相的测量结果。采用 t 检验来评估基于 CT 的测量值与经修正的基于射线照相的测量值之间的差异(α=0.05):结果:基于 CT 和基于 X 光片的 JSW 测量值分别为 3.61±0.72 mm 和 2.18±0.40 mm。基于X光片的关节间隙校正系数为1.69±0.41。校正前,基于 CT 的关节间隙与基于 X 光片的关节间隙之间的差异为 1.43 mm [95% CI: 0.99-1.86 mm; p0.001]。校正后,差异为-0.11毫米[95% CI:-0.63-0.41毫米;P=0.669]:结论:TMC JSW 的影像学校正测量结果与 CT 测量的 JSW 非常吻合。经过体内验证,所开发的方法具有自动、准确测量 TMC JSW 的潜力。
Estimation of radiographic joint space of the trapeziometacarpal joint with computed tomographic validation.
Purpose: Joint space width (JSW) is a common metric used to evaluate joint structure on plain radiographs. For the hand, quantitative techniques are available for evaluation of the JSW of finger joints; however, such techniques have been difficult to establish for the trapeziometacarpal (TMC) joint. This study aimed to develop a validated method for measuring the radiographic joint space of the healthy TMC joint.
Approach: Computed tomographic scans were taken of 15 cadaveric hands. The location of a JSW analysis region on the articular surface of the first metacarpal was established in 3D space and standardized in a 2D projection. The standardized region was applied to simulated radiographic images. A correction factor was defined as the ratio of the CT-based and radiograph-based joint space measurements. Leave-one-out validation was used to correct the radiograph-based measurements. A t-test was used to evaluate the difference between CT-based and corrected radiograph-based measurements ().
Results: The CT-based and radiograph-based measurements of JSW were and , respectively. The correction factor for radiograph-based joint space was . Before correction, the difference between the CT-based and radiograph-based joint space was 1.43 mm [95% CI: ; ]. After correction, the difference was [95% CI: ; ].
Conclusions: Corrected measurements of radiographic TMC JSW agreed well with CT-measured JSW. With in-vivo validation, the developed methodology has potential for automated and accurate radiographic measurement of TMC JSW.
期刊介绍:
JMI covers fundamental and translational research, as well as applications, focused on medical imaging, which continue to yield physical and biomedical advancements in the early detection, diagnostics, and therapy of disease as well as in the understanding of normal. The scope of JMI includes: Imaging physics, Tomographic reconstruction algorithms (such as those in CT and MRI), Image processing and deep learning, Computer-aided diagnosis and quantitative image analysis, Visualization and modeling, Picture archiving and communications systems (PACS), Image perception and observer performance, Technology assessment, Ultrasonic imaging, Image-guided procedures, Digital pathology, Biomedical applications of biomedical imaging. JMI allows for the peer-reviewed communication and archiving of scientific developments, translational and clinical applications, reviews, and recommendations for the field.