饮用含氟量高的砖茶会增加中国藏族骨关节炎的发病率。

IF 2.2 4区医学 Q3 ENVIRONMENTAL SCIENCES

International Journal of Environmental Health Research Pub Date : 2024-11-01 Epub Date: 2024-03-06 DOI:10.1080/09603123.2024.2324936

Xinyue Meng, Hanying Li, Xiaona Liu, Bingyun Li, Yang Liu, Mang Li, Dianjun Sun, Yanmei Yang, Yanhui Gao, Junrui Pei

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引用次数: 0

摘要

藏族人的骨关节炎（OA）发病率高于汉族人，而藏族人有饮用高氟砖茶的习惯。为了探讨饮用砖茶中的氟暴露与 OA 之间的关系，我们进行了一项横断面研究。所有受试者按茶氟化物（TF）和尿氟化物（UF）的四分位数（Q）分为四组。利用逻辑回归模型绘制 ROC 图并得出 OR 值。茶氟化物 Q3 组和 Q4 组的 OA 患病率分别是 Q1 组的 2.2 倍和 2.7 倍，尿氟化物 Q2 组、Q3 组和 Q4 组的 OA 患病率分别是 Q1 组的 3.2 倍、3.5 倍和 4.1 倍。ROC 分析显示，临界值分别为 4.523 毫克/天（TF）和 1.666 毫克/升（UF）。总之，饮用砖茶中过量的氟可能是罹患 OA 的风险因素。

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Drinking brick tea containing high fluoride increases the prevalence of osteoarthritis in Tibetan, China.

The prevalence of osteoarthritis (OA) in Tibetans is higher than that in Han, while Tibetans have a habit of drinking brick tea with high fluoride. A cross-sectional study was conducted to explore the association between fluoride exposure in drinking brick tea and OA. All subjects were divided into four groups by the quartiles (Q) of tea fluoride (TF) and urine fluoride (UF). ROC was plotted and OR were obtained using logistic regression model. The prevalence of OA in the Q3 and Q4 group of TF were 2.2 and 2.7 times higher than in the Q1 group, and the prevalence of OA in the Q2, Q3 and Q4 group of UF were 3.2, 3.5, and 4.1 times higher than in the Q1 group. ROC analysis showed the cutoff values were 4.523 mg/day (TF) and 1.666 mg/L (UF). In conclusion, excessive fluoride in drinking brick tea could be a risk factor for developing OA.

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来源期刊

International Journal of Environmental Health Research 医学-公共卫生、环境卫生与职业卫生

CiteScore

6.70

自引率

3.10%

发文量

134

审稿时长

>12 weeks

期刊介绍： International Journal of Environmental Health Research ( IJEHR ) is devoted to the rapid publication of research in environmental health, acting as a link between the diverse research communities and practitioners in environmental health. Published articles encompass original research papers, technical notes and review articles. IJEHR publishes articles on all aspects of the interaction between the environment and human health. This interaction can broadly be divided into three areas: the natural environment and health – health implications and monitoring of air, water and soil pollutants and pollution and health improvements and air, water and soil quality standards; the built environment and health – occupational health and safety, exposure limits, monitoring and control of pollutants in the workplace, and standards of health; and communicable diseases – disease spread, control and prevention, food hygiene and control, and health aspects of rodents and insects. IJEHR is published in association with the International Federation of Environmental Health and includes news from the Federation of international meetings, courses and environmental health issues.