Josué Cruz-Rodríguez, Josefa Canals-Sans, Carmen Hernández-Martínez, Victoria Arija
{"title":"孕期维生素 B12 状态与可能的产后抑郁之间的关系：ECLIPSES 研究。","authors":"Josué Cruz-Rodríguez, Josefa Canals-Sans, Carmen Hernández-Martínez, Victoria Arija","doi":"10.1080/02646838.2024.2324043","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>B12 vitamin is essential for the functioning of the nervous system and the production of mood-related neurotransmitters. However, information on its association with postpartum depression (PPD) is limited.</p><p><strong>Objective: </strong>To examine the effect of serum vitamin B12 levels during pregnancy on PPD, in healthy pregnant women from the Mediterranean region of Catalonia, Spain.</p><p><strong>Method: </strong>This longitudinal study included a subsample of women at 54 days (7.7 weeks) postpartum (<i>n</i> = 336), who participated in the ECLIPSES Study conducted out in Tarragona, Spain. Maternal concentrations of vitamin B12 were determined in the first and third trimester of pregnancy and sociodemographic, nutritional, and psychological data were collected. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS).</p><p><strong>Results: </strong>The prevalence of probable PPD was 21%. After adjusting for sociodemographic, lifestyle, biochemical parameters, and postpartum characteristics the regression model showed a negative association between EPDS scores and the highest quartile of serum vitamin B12 (first quartile (reference) vs. fourth quartile), (β = -1.267, 95% CI = -2.461, -0.073, <i>p</i> = 0.038).</p><p><strong>Conclusion: </strong>Maintaining a normal-high level of vitamin B12 during early pregnancy can contributes to preventing PPD.</p>","PeriodicalId":47721,"journal":{"name":"Journal of Reproductive and Infant Psychology","volume":null,"pages":null},"PeriodicalIF":2.1000,"publicationDate":"2024-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Association between of vitamin B12 status during pregnancy and probable postpartum depression: the ECLIPSES study.\",\"authors\":\"Josué Cruz-Rodríguez, Josefa Canals-Sans, Carmen Hernández-Martínez, Victoria Arija\",\"doi\":\"10.1080/02646838.2024.2324043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>B12 vitamin is essential for the functioning of the nervous system and the production of mood-related neurotransmitters. However, information on its association with postpartum depression (PPD) is limited.</p><p><strong>Objective: </strong>To examine the effect of serum vitamin B12 levels during pregnancy on PPD, in healthy pregnant women from the Mediterranean region of Catalonia, Spain.</p><p><strong>Method: </strong>This longitudinal study included a subsample of women at 54 days (7.7 weeks) postpartum (<i>n</i> = 336), who participated in the ECLIPSES Study conducted out in Tarragona, Spain. Maternal concentrations of vitamin B12 were determined in the first and third trimester of pregnancy and sociodemographic, nutritional, and psychological data were collected. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS).</p><p><strong>Results: </strong>The prevalence of probable PPD was 21%. After adjusting for sociodemographic, lifestyle, biochemical parameters, and postpartum characteristics the regression model showed a negative association between EPDS scores and the highest quartile of serum vitamin B12 (first quartile (reference) vs. fourth quartile), (β = -1.267, 95% CI = -2.461, -0.073, <i>p</i> = 0.038).</p><p><strong>Conclusion: </strong>Maintaining a normal-high level of vitamin B12 during early pregnancy can contributes to preventing PPD.</p>\",\"PeriodicalId\":47721,\"journal\":{\"name\":\"Journal of Reproductive and Infant Psychology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Reproductive and Infant Psychology\",\"FirstCategoryId\":\"102\",\"ListUrlMain\":\"https://doi.org/10.1080/02646838.2024.2324043\",\"RegionNum\":4,\"RegionCategory\":\"心理学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHOLOGY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Reproductive and Infant Psychology","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1080/02646838.2024.2324043","RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHOLOGY, MULTIDISCIPLINARY","Score":null,"Total":0}
Association between of vitamin B12 status during pregnancy and probable postpartum depression: the ECLIPSES study.
Background: B12 vitamin is essential for the functioning of the nervous system and the production of mood-related neurotransmitters. However, information on its association with postpartum depression (PPD) is limited.
Objective: To examine the effect of serum vitamin B12 levels during pregnancy on PPD, in healthy pregnant women from the Mediterranean region of Catalonia, Spain.
Method: This longitudinal study included a subsample of women at 54 days (7.7 weeks) postpartum (n = 336), who participated in the ECLIPSES Study conducted out in Tarragona, Spain. Maternal concentrations of vitamin B12 were determined in the first and third trimester of pregnancy and sociodemographic, nutritional, and psychological data were collected. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS).
Results: The prevalence of probable PPD was 21%. After adjusting for sociodemographic, lifestyle, biochemical parameters, and postpartum characteristics the regression model showed a negative association between EPDS scores and the highest quartile of serum vitamin B12 (first quartile (reference) vs. fourth quartile), (β = -1.267, 95% CI = -2.461, -0.073, p = 0.038).
Conclusion: Maintaining a normal-high level of vitamin B12 during early pregnancy can contributes to preventing PPD.
期刊介绍：
The Journal of Reproductive and Infant Psychology reports and reviews outstanding research on psychological, behavioural, medical and social aspects of human reproduction, pregnancy and infancy. Medical topics focus on obstetrics and gynaecology, paediatrics and psychiatry. The growing work in relevant aspects of medical communication and medical sociology are also covered. Relevant psychological work includes developmental psychology, clinical psychology, social psychology, behavioural medicine, psychology of women and health psychology. Research into psychological aspects of midwifery, health visiting and nursing is central to the interests of the Journal. The Journal is of special value to those concerned with interdisciplinary issues. As a result, the Journal is of particular interest to those concerned with fundamental processes in behaviour and to issues of health promotion and service organization.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
