桔梗消费者中桔梗使用障碍的流行率。

IF 4.2 3区 医学 Q1 SUBSTANCE ABUSE
Journal of Addiction Medicine Pub Date : 2024-05-01 Epub Date: 2024-03-05 DOI:10.1097/ADM.0000000000001290
Katherine Hill, Oliver Grundmann, Kirsten E Smith, Corneliu N Stanciu
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引用次数: 0

摘要

目的:在美国,桔梗叶产品的消费量越来越大,许多消费者表示他们从使用桔梗中体验到了有益的效果。然而,人们越来越担心经常使用 Kratom 可能会产生依赖性。因此,我们试图使用《精神疾病诊断与统计手册》(DSM-5)中的药物使用障碍诊断标准,评估 "kratom 使用障碍"(KUD)在 kratom 消费者中的流行率:我们的横断面研究在 2023 年 2 月至 5 月期间进行了在线匿名调查。通过非概率抽样调查,我们招募了 18 岁以上、目前食用 kratom 的人群。调查询问了参与者的克瑞托姆消费模式、认为克瑞托姆消费产生的不良影响、合并诊断以及根据克瑞托姆改编的 DSM-5 物质使用障碍的组成部分:在所有样本(样本数 = 2061)中,25.5% 的参与者(样本数 = 525)符合 KUD 标准;最常报告的症状是耐受(样本数 = 427,81.3%)和戒断(样本数 = 357,68.0%)。在对年龄、性别、每天服用克拉托姆的频率以及药物使用障碍或精神疾病史进行调整后,同时被诊断为另一种药物使用障碍的人与未被诊断为另一种药物使用障碍的人相比,符合 KUD 标准的几率高出 2.83 倍(95% CI,2.19-3.67):在这项大型横断面研究中,大多数符合 KUD 诊断标准的参与者被归类为轻度或中度 KUD。与 KUD 相关的个体特征包括男性、年轻、经常服用 kratom 以及合并有精神病和药物使用障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of Kratom Use Disorder Among Kratom Consumers.

Objectives: Kratom leaf products are increasingly consumed in the United States, with many consumers reporting they experience beneficial effects from kratom use. However, there is a growing concern for kratom's potential to result in dependence when used regularly. As such, we sought to assess, using Diagnostic and Statistical Manual of Mental Disorders , (DSM-5) , diagnostic criteria for substance use disorder, the prevalence of "kratom use disorder" (KUD) among kratom consumers.

Methods: Our cross-sectional study used an online, anonymous survey between February and May 2023. Through nonprobability sampling, we recruited people older than 18 years who currently consume kratom. Participants were asked about their kratom consumption patterns, adverse effects perceived to stem from kratom consumption, comorbid diagnoses, and components for a DSM-5 , substance use disorder, adapted for kratom.

Results: Among the total sample ( N = 2061), KUD criteria were met by 25.5% of participants ( n = 525); the most commonly reported symptoms were tolerance ( n = 427, 81.3%) and withdrawal ( n = 357, 68.0%). After adjusting for age, gender, daily frequency of kratom consumption, and history of either a substance use disorder or a mental health condition, those with a concurrent diagnosis of another substance use disorder had 2.83 times higher odds of meeting KUD criteria (95% CI, 2.19-3.67) compared with those without one.

Conclusions: In this large cross-sectional study, most participants who met the criteria for a KUD diagnosis were categorized as having a mild or moderate KUD. Individual characteristics associated with KUD were related to being male, young, consuming kratom frequently, and having psychiatric and substance use disorder comorbidities.

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来源期刊
Journal of Addiction Medicine
Journal of Addiction Medicine 医学-药物滥用
CiteScore
6.10
自引率
9.10%
发文量
260
审稿时长
>12 weeks
期刊介绍: The mission of Journal of Addiction Medicine, the official peer-reviewed journal of the American Society of Addiction Medicine, is to promote excellence in the practice of addiction medicine and in clinical research as well as to support Addiction Medicine as a mainstream medical sub-specialty. Under the guidance of an esteemed Editorial Board, peer-reviewed articles published in the Journal focus on developments in addiction medicine as well as on treatment innovations and ethical, economic, forensic, and social topics including: •addiction and substance use in pregnancy •adolescent addiction and at-risk use •the drug-exposed neonate •pharmacology •all psychoactive substances relevant to addiction, including alcohol, nicotine, caffeine, marijuana, opioids, stimulants and other prescription and illicit substances •diagnosis •neuroimaging techniques •treatment of special populations •treatment, early intervention and prevention of alcohol and drug use disorders •methodological issues in addiction research •pain and addiction, prescription drug use disorder •co-occurring addiction, medical and psychiatric disorders •pathological gambling disorder, sexual and other behavioral addictions •pathophysiology of addiction •behavioral and pharmacological treatments •issues in graduate medical education •recovery •health services delivery •ethical, legal and liability issues in addiction medicine practice •drug testing •self- and mutual-help.
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