蜂胶是治疗肥胖症的潜在抗致肥剂吗?

IF 4.6 3区 医学 Q1 NUTRITION & DIETETICS
Current Nutrition Reports Pub Date : 2024-06-01 Epub Date: 2024-03-04 DOI:10.1007/s13668-024-00524-0
Nilüfer Acar Tek, Şerife Akpınar Şentüre, Nursena Ersoy
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引用次数: 0

摘要

审查目的:蜂胶是一种蜂产品,已有数千年的使用历史。二十世纪对蜂胶的化学成分和生物活性进行了研究,不同地区的蜂胶化学成分和生物活性可能有所不同。蜂胶多酚可通过解偶联蛋白-1 和肌酸激酶代谢途径诱导棕色和米色脂肪组织产生热量。本综述全面研究了蜂胶的结构和生物特性,并深入探讨了蜂胶在体重管理方面大有可为的潜在策略:最近的研究结果:蜂胶通过提高总体能量消耗,可能有助于控制体重。此外,蜂胶成分中的酚类成分青蒿素 C、槲皮素、儿茶素和绿原酸可通过刺激交感神经系统、促进白色脂肪组织褐变、引发 AMP 激活蛋白激酶活化和线粒体生物生成,从而起到抗致肥作用。蜂胶是一种天然产品,可有效预防当代流行的肥胖症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is Propolis a Potential Anti-Obesogenic Agent for Obesity?

Purpose of review: Propolis is a bee product that has been used for thousands of years. The chemical composition and biological activity of propolis, which has been investigated in the twentieth century, may vary according to location. Propolis polyphenols can induce thermogenesis in brown and beige fat tissue via the uncoupled protein-1 and creatinine kinase metabolic pathways. This review provides a comprehensive investigation of the structural and biological properties of propolis and provides insights into their promising potential strategies in body weight management.

Recent findings: By raising overall energy expenditure, it might lead to body weight management. Furthermore, the phenolic components artepillin C, quercetin, catechin, and chlorogenic acid found in its composition may have anti-obesogenic effect by stimulating the sympathetic nervous system, enhancing browning in white adipose tissue, and triggering AMP-activated protein kinase activation and mitochondrial biogenesis. Propolis, a natural product, is effective in preventing obesity which is a contemporary pandemic.

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来源期刊
Current Nutrition Reports
Current Nutrition Reports Agricultural and Biological Sciences-Food Science
CiteScore
7.70
自引率
2.00%
发文量
59
期刊介绍: This journal aims to provide comprehensive review articles that emphasize significant developments in nutrition research emerging in recent publications. By presenting clear, insightful, balanced contributions by international experts, the journal intends to discuss the influence of nutrition on major health conditions such as diabetes, cardiovascular disease, cancer, and obesity, as well as the impact of nutrition on genetics, metabolic function, and public health. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas across the field. Section Editors select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 25 internationally diverse members reviews the annual table of contents, suggests topics of special importance to their country/region, and ensures that topics and current and include emerging research.
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