黄芩苷治疗潜力的最新进展:最新综述。

IF 4.8 3区 化学 Q1 CHEMISTRY, MEDICINAL
Yifei Xie, Guotong Sun, Yue Tao, Wen Zhang, Shiying Yang, Li Zhang, Yang Lu, Guanhua Du
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引用次数: 0

摘要

黄芩苷广泛分布于唇形科植物黄芩和菊科植物金盏花中,属于黄酮类化合物。黄芩苷具有广泛的药理活性,被广泛用于治疗脑梗塞、心绞痛、脑血栓、冠心病等疾病。它是一种极具研究和开发前景的天然产物。近年来,随着研究的深入,研究人员发现野生黄芩苷在抗肿瘤、抗炎、抗氧化、抗病毒、治疗代谢性疾病、保护肾脏等方面也有很好的治疗效果。癌症治疗涉及胶质瘤、乳腺癌、肺癌、肾癌、结肠癌等。本文总结了近年来黄芩苷的来源、药理作用、体内和体外模型,分析了黄芩苷的研究现状和未来发展方向。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Current advances on the therapeutic potential of scutellarin: an updated review

Current advances on the therapeutic potential of scutellarin: an updated review

Scutellarin is widely distributed in Scutellaria baicalensis, family Labiatae, and Calendula officinalis, family Asteraceae, and belongs to flavonoids. Scutellarin has a wide range of pharmacological activities, it is widely used in the treatment of cerebral infarction, angina pectoris, cerebral thrombosis, coronary heart disease, and other diseases. It is a natural product with great research and development prospects. In recent years, with in-depth research, researchers have found that wild scutellarin also has good therapeutic effects in anti-tumor, anti-inflammatory, anti-oxidation, anti-virus, treatment of metabolic diseases, and protection of kidney. The cancer treatment involves glioma, breast cancer, lung cancer, renal cancer, colon cancer, and so on. In this paper, the sources, pharmacological effects, in vivo and in vitro models of scutellarin were summarized in recent years, and the current research status and future direction of scutellarin were analyzed.

Graphical Abstract

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来源期刊
Natural Products and Bioprospecting
Natural Products and Bioprospecting CHEMISTRY, MEDICINAL-
CiteScore
8.30
自引率
2.10%
发文量
39
审稿时长
13 weeks
期刊介绍: Natural Products and Bioprospecting serves as an international forum for essential research on natural products and focuses on, but is not limited to, the following aspects: Natural products: isolation and structure elucidation Natural products: synthesis Biological evaluation of biologically active natural products Bioorganic and medicinal chemistry Biosynthesis and microbiological transformation Fermentation and plant tissue cultures Bioprospecting of natural products from natural resources All research articles published in this journal have undergone rigorous peer review. In addition to original research articles, Natural Products and Bioprospecting publishes reviews and short communications, aiming to rapidly disseminate the research results of timely interest, and comprehensive reviews of emerging topics in all the areas of natural products. It is also an open access journal, which provides free access to its articles to anyone, anywhere.
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