小麦(Triticum aestivum L.)耐旱性的全基因组关联研究确定了 SNP 标记和候选基因。

IF 2.3 3区 生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY
Sina Nouraei, Md Sultan Mia, Hui Liu, Neil C Turner, Guijun Yan
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引用次数: 0

摘要

干旱胁迫对全球小麦生产构成严重威胁,因此有必要深入探讨耐旱相关性状的遗传基础。本研究利用 90 K SNP 阵列进行了全基因组关联分析,揭示了小麦耐旱性相关关键性状(即株高、根长、根和芽干重)的遗传决定因素。利用混合线性模型(MLM)方法对 125 个小麦品种进行了水分充足和干旱胁迫处理,我们发现了 53 个 SNPs 与目标性状的胁迫易感性(SSI)和耐受性指数(STI)显著相关。值得注意的是,2A 和 3B 染色体分别有 10 个和 9 个相关标记。在 17 条染色体上,确定了 44 个独特的候选基因,主要位于 1A、1B、1D、2A、3A、3B、4A、6A、6B、7A、7B 和 7D 染色体的远端。这些基因与植物生长、发育和胁迫反应相关的多种功能有关,为今后的研究提供了丰富的资源。在 2AS 和 3BL 染色体臂的特定区域出现了一种聚类模式,特别是有 7 个基因与植株高度的 SSI 相关,4 个基因与植株高度和芽干重的 STI 相关。此外,多聚半乳糖醛酸酶、辅苷相关蛋白 1、肽变形酶和受体样激酶等编码基因的共用突显了植株高度和芽干重之间的相互联系。总之,我们的研究结果深入揭示了小麦耐旱性的分子机制,为进一步探索和作物改良战略确定了有前景的基因组位点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Genome-wide association study of drought tolerance in wheat (Triticum aestivum L.) identifies SNP markers and candidate genes.

Genome-wide association study of drought tolerance in wheat (Triticum aestivum L.) identifies SNP markers and candidate genes.

Drought stress poses a severe threat to global wheat production, necessitating an in-depth exploration of the genetic basis for drought tolerance associated traits. This study employed a 90 K SNP array to conduct a genome-wide association analysis, unravelling genetic determinants of key traits related to drought tolerance in wheat, namely plant height, root length, and root and shoot dry weight. Using the mixed linear model (MLM) method on 125 wheat accessions subjected to both well-watered and drought stress treatments, we identified 53 SNPs significantly associated with stress susceptibility (SSI) and tolerance indices (STI) for the targeted traits. Notably, chromosomes 2A and 3B stood out with ten and nine associated markers, respectively. Across 17 chromosomes, 44 unique candidate genes were pinpointed, predominantly located on the distal ends of 1A, 1B, 1D, 2A, 3A, 3B, 4A, 6A, 6B, 7A, 7B, and 7D chromosomes. These genes, implicated in diverse functions related to plant growth, development, and stress responses, offer a rich resource for future investigation. A clustering pattern emerged, notably with seven genes associated with SSI for plant height and four genes linked to both STI of plant height and shoot dry weight, converging on specific regions of chromosome arms of 2AS and 3BL. Additionally, shared genes encoding polygalacturonase, auxilin-related protein 1, peptide deformylase, and receptor-like kinase underscored the interconnectedness between plant height and shoot dry weight. In conclusion, our findings provide insights into the molecular mechanisms governing wheat drought tolerance, identifying promising genomic loci for further exploration and crop improvement strategies.

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来源期刊
Molecular Genetics and Genomics
Molecular Genetics and Genomics 生物-生化与分子生物学
CiteScore
5.10
自引率
3.20%
发文量
134
审稿时长
1 months
期刊介绍: Molecular Genetics and Genomics (MGG) publishes peer-reviewed articles covering all areas of genetics and genomics. Any approach to the study of genes and genomes is considered, be it experimental, theoretical or synthetic. MGG publishes research on all organisms that is of broad interest to those working in the fields of genetics, genomics, biology, medicine and biotechnology. The journal investigates a broad range of topics, including these from recent issues: mechanisms for extending longevity in a variety of organisms; screening of yeast metal homeostasis genes involved in mitochondrial functions; molecular mapping of cultivar-specific avirulence genes in the rice blast fungus and more.
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