{"title":"食用菌提取β-葡聚糖的化学结构特征及其生物活性","authors":"Ryan Haryo Setyawan , Ardi Ardiansyah , Nissa Nurfajrin Solihat , Rizki Rabeca Elfirta , Iwan Saskiawan , Riska Surya Ningrum , Nunuk Widhyastuti , Kasirah Kasirah , Budi Saksono , Dewi Sondari , Hakiki Melanie , Bambang Nurhadi , Riksfardini Annisa Ermawar","doi":"10.1016/j.bcdf.2024.100411","DOIUrl":null,"url":null,"abstract":"<div><p>Beta-glucan has been known for its bioactivity such as for anticancer, antioxidant and antimicrobial agent. Naturally, beta-glucan is chemical structurally diverse in various beta-glucan sources such as edible mushroom. The chemical structure diversity of edible mushroom-origin beta-glucan has not yet been studied for its correlation with their bioactivity. Hence, this study observed the chemical structure and the bioactivity of beta-glucan extracted from five different edible mushrooms, which are <em>Pleurotus ostreatus, Ganoderma lucidum, Volvariella volvacea, Agaricus bisporus,</em> and <em>Auricularia auricula</em>. <em>A. auricula</em> contained the highest beta-glucan among the other edible mushroom (26.47 ± 3.45 g/100g). While <em>V. volvacea</em> beta-glucan extract possessed the highest cytotoxicity against breast cancer cells which enabled to inhibit 126.42% of cancer cells growth. It is shown that each edible mushroom has a different content of beta-glucan and bioactivity.</p></div>","PeriodicalId":38299,"journal":{"name":"Bioactive Carbohydrates and Dietary Fibre","volume":"31 ","pages":"Article 100411"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemical structure characterization of edible mushroom-extracted beta-glucan and its bioactivity\",\"authors\":\"Ryan Haryo Setyawan , Ardi Ardiansyah , Nissa Nurfajrin Solihat , Rizki Rabeca Elfirta , Iwan Saskiawan , Riska Surya Ningrum , Nunuk Widhyastuti , Kasirah Kasirah , Budi Saksono , Dewi Sondari , Hakiki Melanie , Bambang Nurhadi , Riksfardini Annisa Ermawar\",\"doi\":\"10.1016/j.bcdf.2024.100411\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Beta-glucan has been known for its bioactivity such as for anticancer, antioxidant and antimicrobial agent. Naturally, beta-glucan is chemical structurally diverse in various beta-glucan sources such as edible mushroom. The chemical structure diversity of edible mushroom-origin beta-glucan has not yet been studied for its correlation with their bioactivity. Hence, this study observed the chemical structure and the bioactivity of beta-glucan extracted from five different edible mushrooms, which are <em>Pleurotus ostreatus, Ganoderma lucidum, Volvariella volvacea, Agaricus bisporus,</em> and <em>Auricularia auricula</em>. <em>A. auricula</em> contained the highest beta-glucan among the other edible mushroom (26.47 ± 3.45 g/100g). While <em>V. volvacea</em> beta-glucan extract possessed the highest cytotoxicity against breast cancer cells which enabled to inhibit 126.42% of cancer cells growth. It is shown that each edible mushroom has a different content of beta-glucan and bioactivity.</p></div>\",\"PeriodicalId\":38299,\"journal\":{\"name\":\"Bioactive Carbohydrates and Dietary Fibre\",\"volume\":\"31 \",\"pages\":\"Article 100411\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioactive Carbohydrates and Dietary Fibre\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2212619824000111\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioactive Carbohydrates and Dietary Fibre","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212619824000111","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chemical structure characterization of edible mushroom-extracted beta-glucan and its bioactivity
Beta-glucan has been known for its bioactivity such as for anticancer, antioxidant and antimicrobial agent. Naturally, beta-glucan is chemical structurally diverse in various beta-glucan sources such as edible mushroom. The chemical structure diversity of edible mushroom-origin beta-glucan has not yet been studied for its correlation with their bioactivity. Hence, this study observed the chemical structure and the bioactivity of beta-glucan extracted from five different edible mushrooms, which are Pleurotus ostreatus, Ganoderma lucidum, Volvariella volvacea, Agaricus bisporus, and Auricularia auricula. A. auricula contained the highest beta-glucan among the other edible mushroom (26.47 ± 3.45 g/100g). While V. volvacea beta-glucan extract possessed the highest cytotoxicity against breast cancer cells which enabled to inhibit 126.42% of cancer cells growth. It is shown that each edible mushroom has a different content of beta-glucan and bioactivity.
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