通过对一名重度震颤患者实施丘脑切除术进行补救治疗,脑深部刺激电极断裂导致震颤反弹且阻抗正常:病例报告

IF 0.4 Q4 CLINICAL NEUROLOGY
Takeshi Hashikawa , Galih Indra Permana , Takashi Morishita , Takayuki Koga , Hideaki Tanaka , Hiromasa Kobayashi , Hiroshi Abe
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引用次数: 0

摘要

背景深部脑刺激(DBS)已被证明是治疗本质性震颤和其他运动障碍的有效方法。然而,与硬件相关的并发症限制了其疗效。DBS 中的导线断裂通常发生在高危患者的颈椎部位。病例报告:一位 89 岁的女性患者曾接受过腹侧中间核双侧 DBS 治疗,后出现右上肢震颤加重。检查显示阻抗正常。增加刺激并未改善她的震颤症状。放射检查发现导线断裂。鉴于患者的手术风险较高,我们对其进行了丘脑切开术,然后从左侧腹中核取出电极导线。结论:导线断裂是 DBS 硬件相关的并发症,如果患者主诉突然出现反跳性震颤,即使电阻抗值在正常范围内,也应怀疑该病。应进行影像学检查,对于因全身麻醉风险而无法手术的患者,可选择丘脑切开术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tremor Rebound Due to a Deep Brain Stimulation Electrode Fracture with Normal Impedance Treated by Rescue Thalamotomy in a Patient with Essential Tremor: A Case Report

Background

Deep brain stimulation (DBS) has been shown to be an effective treatment for essential tremor and other movement disorders. However, hardware-related complications have limited its efficacy. Lead fracture in DBS typically occurs in the cervical area in high-risk patients. Surgical revision is needed to relieve worsened tremor symptoms in these cases.

Case Report

An 89-year-old woman with a history of bilateral DBS to the ventralis intermedius nucleus for essential tremor presented with worsened tremor in the right upper limb. Examination revealed normal impedance. Increased stimulation did not improve her tremor symptoms. Radiographic examination revealed lead fracture. Given the patient’s high surgical risk we performed thalamotomy followed by extraction of the electrode lead from the left ventralis intermedius nucleus.

Conclusion

Lead fracture is a hardware-related complication of DBS and should be suspected if a patient complains of sudden-onset rebound tremor, even when electrical impedance values are within the normal range. Imaging studies should be performed, and thalamotomy may be an option for patients in whom the risks of general anaesthesia preclude surgery.

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CiteScore
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