Yaobing Chen, Jinli Zhang, Lijun Yuan, Huifang Hu, Tianze Li, Yang Zhao, Yuying Wu, Mengmeng Wang, Weifeng Huo, Yajuan Gao, Yamin Ke, Longkang Wang, Wenkai Zhang, Xueru Fu, Xi Li, Fulan Hu, Ming Zhang, Liang Sun, Dongsheng Hu
{"title":"肥胖与儿童和青少年患抑郁症的风险：观察性研究的荟萃分析。","authors":"Yaobing Chen, Jinli Zhang, Lijun Yuan, Huifang Hu, Tianze Li, Yang Zhao, Yuying Wu, Mengmeng Wang, Weifeng Huo, Yajuan Gao, Yamin Ke, Longkang Wang, Wenkai Zhang, Xueru Fu, Xi Li, Fulan Hu, Ming Zhang, Liang Sun, Dongsheng Hu","doi":"10.1111/cch.13237","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Purpose</h3>\n \n <p>This meta-analysis evaluated the relationship between overweight/obesity and depressive disorders in children and adolescents.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>We examined the databases of PubMed, Embase and Web of Science for pertinent observational studies released up until 20 February 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) of obesity and overweight with depressive disorder were calculated by means of random-effects models. The Newcastle-Ottawa Quality Assessment Scale and Agency for Healthcare Research and Quality scale were adopted to evaluate the study quality.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Finally, for this meta-analysis, we evaluated 22 observational publications covering 175 135 participants (5 cohort study articles, 1 case–control study article and 16 cross-sectional study articles). A significant positive association was found between obesity and the risk of depression (RR 1.32, 95% CI 1.09–1.60, <i>I</i><sup>2</sup> = 79.90%, <i>P</i><sub>heterogeneity</sub> < 0.001) and in the association between obesity and depressive symptoms (RR 1.16, 95% CI: 1.00–1.35, <i>I</i><sup>2</sup> = 25.0%, <i>P</i><sub>heterogeneity</sub> = 0.247). On sensitivity analysis, the pooled RRs remained robust. Subgroup analysis indicated that obese children and teenagers in western countries were more prone to depression.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Evidence from this meta-analysis, based on observational studies, supported the idea that obese children and adolescents are more likely to experience depression and depressive symptoms.</p>\n </section>\n </div>","PeriodicalId":55262,"journal":{"name":"Child Care Health and Development","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Obesity and risk of depressive disorder in children and adolescents: A meta-analysis of observational studies\",\"authors\":\"Yaobing Chen, Jinli Zhang, Lijun Yuan, Huifang Hu, Tianze Li, Yang Zhao, Yuying Wu, Mengmeng Wang, Weifeng Huo, Yajuan Gao, Yamin Ke, Longkang Wang, Wenkai Zhang, Xueru Fu, Xi Li, Fulan Hu, Ming Zhang, Liang Sun, Dongsheng Hu\",\"doi\":\"10.1111/cch.13237\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Purpose</h3>\\n \\n <p>This meta-analysis evaluated the relationship between overweight/obesity and depressive disorders in children and adolescents.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>We examined the databases of PubMed, Embase and Web of Science for pertinent observational studies released up until 20 February 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) of obesity and overweight with depressive disorder were calculated by means of random-effects models. The Newcastle-Ottawa Quality Assessment Scale and Agency for Healthcare Research and Quality scale were adopted to evaluate the study quality.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>Finally, for this meta-analysis, we evaluated 22 observational publications covering 175 135 participants (5 cohort study articles, 1 case–control study article and 16 cross-sectional study articles). A significant positive association was found between obesity and the risk of depression (RR 1.32, 95% CI 1.09–1.60, <i>I</i><sup>2</sup> = 79.90%, <i>P</i><sub>heterogeneity</sub> < 0.001) and in the association between obesity and depressive symptoms (RR 1.16, 95% CI: 1.00–1.35, <i>I</i><sup>2</sup> = 25.0%, <i>P</i><sub>heterogeneity</sub> = 0.247). On sensitivity analysis, the pooled RRs remained robust. Subgroup analysis indicated that obese children and teenagers in western countries were more prone to depression.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Evidence from this meta-analysis, based on observational studies, supported the idea that obese children and adolescents are more likely to experience depression and depressive symptoms.</p>\\n </section>\\n </div>\",\"PeriodicalId\":55262,\"journal\":{\"name\":\"Child Care Health and Development\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Child Care Health and Development\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cch.13237\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Child Care Health and Development","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cch.13237","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
Obesity and risk of depressive disorder in children and adolescents: A meta-analysis of observational studies
Purpose
This meta-analysis evaluated the relationship between overweight/obesity and depressive disorders in children and adolescents.
Methods
We examined the databases of PubMed, Embase and Web of Science for pertinent observational studies released up until 20 February 2022. The pooled relative risks (RRs) and 95% confidence intervals (CIs) of obesity and overweight with depressive disorder were calculated by means of random-effects models. The Newcastle-Ottawa Quality Assessment Scale and Agency for Healthcare Research and Quality scale were adopted to evaluate the study quality.
Results
Finally, for this meta-analysis, we evaluated 22 observational publications covering 175 135 participants (5 cohort study articles, 1 case–control study article and 16 cross-sectional study articles). A significant positive association was found between obesity and the risk of depression (RR 1.32, 95% CI 1.09–1.60, I2 = 79.90%, Pheterogeneity < 0.001) and in the association between obesity and depressive symptoms (RR 1.16, 95% CI: 1.00–1.35, I2 = 25.0%, Pheterogeneity = 0.247). On sensitivity analysis, the pooled RRs remained robust. Subgroup analysis indicated that obese children and teenagers in western countries were more prone to depression.
Conclusion
Evidence from this meta-analysis, based on observational studies, supported the idea that obese children and adolescents are more likely to experience depression and depressive symptoms.
期刊介绍：
Child: care, health and development is an international, peer-reviewed journal which publishes papers dealing with all aspects of the health and development of children and young people. We aim to attract quantitative and qualitative research papers relevant to people from all disciplines working in child health. We welcome studies which examine the effects of social and environmental factors on health and development as well as those dealing with clinical issues, the organization of services and health policy. We particularly encourage the submission of studies related to those who are disadvantaged by physical, developmental, emotional and social problems. The journal also aims to collate important research findings and to provide a forum for discussion of global child health issues.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
