预防胎盘早剥导致死产的潜在方法：日本地区人口研究。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-12-01 Epub Date: 2024-02-25 DOI:10.1080/14767058.2024.2321485

Makiko Kasahara, Shigeki Koshida, Shinsuke Tokoro, Daisuke Katsura, Shunichiro Tsuji, Takashi Murakami, Kentaro Takahashi

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引用次数: 0

摘要

目的：胎盘早剥与不良围产期结局有关，包括胎儿宫内死亡，进而导致死胎。然而，很少有研究证明胎盘早剥可预防死胎。因此，我们通过回顾本地区的所有死胎，评估了预防胎盘早剥导致死胎的可能性：本研究回顾了 2010 年至 2019 年日本滋贺县妊娠 22 周后的所有死胎，不包括致死性疾病。我们评估了 350 例死胎，包括胎盘早剥和未发生胎盘早剥的死胎：结果：有 32 例死胎伴有 PA，318 例没有胎盘早剥。有胎盘早剥的患者预防死产的概率明显高于无胎盘早剥的患者（30% vs. 8%，p 结论：有胎盘早剥的患者中，有部分死产是由胎盘早剥引起的：胎盘早剥导致的一些死产是可以预防的。我们建议改进围产期母婴护理和围产期紧急转运系统。

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Potential prevention of stillbirth caused by placental abruption: a regional population-based study in Japan.

Objective: Placental abruption is associated with adverse perinatal outcomes including intrauterine fetal demise, which subsequently results in stillbirth. However, few studies have demonstrated the preventability of stillbirth due to placental abruption. Therefore, we evaluated the possibility of preventing stillbirth caused by placental abruption by reviewing all stillbirths in our region.

Methods: This study reviewed all stillbirths after 22 weeks of gestation in Shiga Prefecture, Japan from 2010 to 2019, excluding lethal disorders. We evaluated 350 stillbirth cases, with and without placental abruption.

Results: There were 32 stillbirths with PA and 318 without placental abruption. The probability of preventing stillbirth was significantly higher in patients with placental abruption than in those without (30% vs. 8%, p < 0.001). We also determined the recommendations for preventing stillbirths with placental abruption.

Conclusion: Some stillbirths caused by placental abruption can be prevented. We recommend improvements to perinatal maternal-fetal care and perinatal emergency transport systems.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.