专家对 "EVER-Vilda "维达列汀疗效和合理性的电子评估:印度视角。

IF 2.7 Q3 ENDOCRINOLOGY & METABOLISM
Sanjay Kalra, Abdul Hamid Zargar, G R Sridhar, Ashok Kumar Das, Jamal Ahmed, Jagdish Chander Mohan, G Vijayakumar, Ajay Kumar, Rakesh Kumar Sahay, Vageesh Ayer, Kaushik Pandit, Ganapathi Bantwal, Arun Srinivas, A G Unnikrishnan, Sushil Jindal, Saumitra Ray, Manash P Baruah, Kajal Ganguly, Sachin Mittal, Ameya Joshi, Joe George, Ganesh Hk, Nitin Kapoor, Santosh Ramakrishnan, Chetan Shah, Atul Dhingra, Balram Sharma
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引用次数: 0

摘要

维达列汀是一种二肽基肽酶-4(DPP-4)抑制剂,单药、双药或三药联合治疗可有效降低 2 型糖尿病(T2DM)患者的 HbA1c 水平。在印度,维达列汀是 T2DM 患者的常用处方药,因为它能降低血糖偏移的平均幅度(MAGE),低血糖风险较低,而且不影响体重。维达列汀和二甲双胍的早期联合疗法对 T2DM 患者有效且耐受性良好,与年龄和种族无关。鉴于维达列汀已有的数据和最新出现的临床证据,一组内分泌科医生、糖尿病医生和心脏病医生召开了专家组会议,讨论维达列汀在 T2DM 治疗中的作用和各种组合。本实用文件旨在指导内科医生和专科医生使用不同强度和剂型的维达列汀开始和加强 T2DM 治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Expert eValuation of Efficacy and Rationality of Vildagliptin "EVER-Vilda": An Indian Perspective.

Vildagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor is effective in reducing HbA1c levels in patients with type 2 diabetes (T2DM) when administered as monotherapy, dual or triple combination therapy. In India, Vildagliptin is commonly prescribed in T2DM patients because it reduces mean amplitude of glycemic excursion (MAGE), has lower risk of hypoglycemia and is weight neutral. Early combination therapy with vildagliptin and metformin is effective and well-tolerated in patients with T2DM, regardless of age or ethnicity. In view of already existing data on vildagliptin and the latest emerging clinical evidence, a group of endocrinologists, diabetologists and cardiologists convened for an expert group meeting to discuss the role and various combinations of vildagliptin in T2DM management. This practical document aims to guide Physicians and Specialists regarding the different available strengths and formulations of vildagliptin for the initiation and intensification of T2DM therapy.

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来源期刊
CiteScore
4.30
自引率
0.00%
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15
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8 weeks
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