病毒感染中的铁突变：潜在的治疗靶点

IF 2.5 4区生物学 Q3 MICROBIOLOGY

Future microbiology Pub Date : 2024-01-01 Epub Date: 2024-02-27 DOI:10.2217/fmb-2023-0186

Liqiong Ding

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引用次数: 0

摘要

铁中毒是一种依赖于铁的程序性细胞死亡，其特点是细胞内铁积累、谷胱甘肽耗竭、谷胱甘肽过氧化物酶失活和脂质过氧化。近年来，越来越多的研究表明病毒感染与铁中毒之间存在密切联系。本文综述了铁氧化在病毒感染中的潜在作用和机制，这些发现将有助于病毒的预防和治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Ferroptosis in viral infection: a potential therapeutic target.

Ferroptosis, known as a type of programmed cell death that is iron dependent, is characterized by intracellular iron accumulation, glutathione depletion, glutathione peroxidase inactivation and lipid peroxidation. More and more research in recent years has demonstrated the tight connection between viral infections and ferroptosis. This article reviews the potential role and mechanism of ferroptosis in viral infection, and these findings will help in the prevention and treatment of the virus.

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来源期刊

Future microbiology 生物-微生物学

CiteScore

4.90

自引率

3.20%

发文量

134

审稿时长

6-12 weeks

期刊介绍： Future Microbiology delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this increasingly important and vast area of research.