日本的一项纵向研究:初产妇的产前抑郁症状、焦虑和唾液催产素水平可预测产后早期的母婴亲子关系

IF 3.2 3区 医学 Q2 PSYCHIATRY
Hitomi Kanekasu, Yachiyo Shiraiwa, Shu Taira, Hiroko Watanabe
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引用次数: 0

摘要

目的 据报道,母婴亲子关系的失败预示着父母的虐待行为。母婴亲子关系对预防虐待儿童非常重要。本研究旨在调查产前抑郁症状、焦虑、皮质醇和催产素水平与产后母婴亲子关系之间的关系。方法受试者在怀孕后三个月填写一份自我报告的产前问卷,其中包括爱丁堡产后抑郁量表(EPDS)和国家特质焦虑量表(STAI)。在怀孕后三个月采集了血液和唾液。测量血浆中的皮质醇水平和唾液中的催产素水平。在产后 2-5 天、1 个月和 3 个月分别进行了产后问卷调查,包括母婴关系量表(MIBS)。研究采用多元线性回归和广义估计方程(GEE)进行分析。分别有 21.2% 和 28.8% 的初产妇出现产前抑郁症状(EPDS ≥ 9)和焦虑症状(STAI-S ≥ 42)。皮质醇和催产素水平的中位数分别为 21.0 µg/dL 和 30.4 pg/mL。多变量线性回归显示,产后社会支持、产前抑郁症状、焦虑和唾液催产素水平可预测产后 2-5 天的 MIBS 分数。产后 1 个月时,家庭收入、流产史、产后社会支持和产前焦虑可预测 MIBS 分数。产后 3 个月时,只有产后社会支持能预测 MIBS 分数。GEE 结果显示,产前焦虑、催产素水平、产后时间、家庭收入和产后社会支持与 MIBS 评分相关。产前焦虑也会导致产后 1 个月母婴关系恶化。测量产前抑郁症状、焦虑和唾液催产素水平可在产后早期评估母婴结合失败的风险,并在孕期进行干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Primiparas’ prenatal depressive symptoms, anxiety, and salivary oxytocin level predict early postnatal maternal–infant bonding: a Japanese longitudinal study

Primiparas’ prenatal depressive symptoms, anxiety, and salivary oxytocin level predict early postnatal maternal–infant bonding: a Japanese longitudinal study

Purpose

It was reported that maternal-infant bonding failure predicts abusive parenting. Maternal-infant bonding is important to prevent child abuse. This study aimed to investigate the association between prenatal depressive symptoms, anxiety, cortisol, and oxytocin levels, and postnatal maternal–infant bonding.

Methods

The participants completed a self-report prenatal questionnaire that included the Edinburgh Postnatal Depression Scale (EPDS) and State-Trait Anxiety Inventory (STAI) in the second trimester. Blood and saliva were collected in the second trimester. Cortisol levels were measured in plasma, while oxytocin levels were measured in saliva. Postnatal questionnaires, including the Mother-to-Infant Bonding Scale (MIBS), were administered at 2–5 days, 1 month, and 3 months postpartum. Multiple linear regression and generalized estimating equation (GEE) were conducted for analysis.

Results

Sixty-six primiparas participated in the study. Prenatal depressive symptoms (EPDS ≥ 9) and anxiety (STAI-S ≥ 42) were observed in 21.2% and 28.8% of the participants, respectively. The median cortisol and oxytocin levels were 21.0 µg/dL and 30.4 pg/mL, respectively. Multivariate linear regression showed that postnatal social support, prenatal depressive symptoms, anxiety, and salivary oxytocin levels predicted MIBS scores at 2–5 days postpartum. At 1 month postpartum, household income, history of miscarriage, postnatal social support, and prenatal anxiety predicted MIBS scores. At 3 months postpartum, only postnatal social support predicted MIBS scores. The results of GEE showed that prenatal anxiety, oxytocin levels, postpartum period, household income, and postpartum social support were associated with MIBS scores.

Conclusion

Prenatal depressive symptoms, anxiety, and lower salivary oxytocin levels were predicted to worsen maternal–infant bonding at 2–5 days postpartum. Prenatal anxiety was predicted to cause the same 1 month postpartum. Measuring prenatal depressive symptoms, anxiety, and salivary oxytocin levels may render the assessment of the risk of maternal–infant bonding failure during the early postpartum period and intervene during pregnancy possible.

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来源期刊
Archives of Women's Mental Health
Archives of Women's Mental Health 医学-精神病学
CiteScore
8.00
自引率
4.40%
发文量
83
审稿时长
6-12 weeks
期刊介绍: Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.
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