女性下肢血流闭塞会增加全身加压反应,但不会增加肱动脉血流的重新分布。

IF 1.3 4区 医学 Q4 PHYSIOLOGY
Abby R. Fleming, Hayley V. MacDonald, Samuel L. Buckner, Lee J. Winchester
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引用次数: 0

摘要

本研究旨在调查两种常用的临床血流限制(BFR)压力在女性静息时和之后的全身血流动力学和血管变化。有关 BFR 对血流动力学和全身血管变化的独立影响的数据极少,尤其是在女性中。因此,本研究调查了两种常用压力(50% 和 80% 的肢体闭塞压力 [LOP])在静息状态下 BFR 引起的加压反应和全身血流重新分布的变化。15 名女性(22.1 ± 4.2 岁)完成了两次随机训练,包括在 50% 或 80% LOP 下进行 8 分钟的双侧下肢限制,然后在放气后进行 8 分钟的恢复训练。使用重复测量方差分析法测试了血管(动脉直径 [DIA]、时间平均速度 [TAMV]、体积流量 [VF] 和面积)和血液动力学(心率 [HR] 和血压)指标随时间(闭塞前、闭塞中和闭塞后)和不同疗程(50% 与 80% LOP)的变化。重复测量相关性(rrm )量化了 BFR 诱导的血液动力学和血管反应之间常见的个体内关联。在 50% LOP 期间,心率从基线上升,并在恢复期(p rm = 0.32-0.70,p rm = 0.38)和 TAMV(rrm = 0.43)期间保持升高,并与胫骨 VF(rrm = -0.36)和 TAMV(rrm = -0.30)呈负相关(p rm = -0.40)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Lower limb blood flow occlusion increases systemic pressor response without increasing brachial arterial blood flow redistribution in women

This study was conducted to investigate the systemic hemodynamic and vascular changes in women during and after two commonly used clinical blood flow restriction (BFR) pressures at rest. There are minimal data regarding the independent effects of BFR on hemodynamic and systemic vascular changes due to pressor response, particularly among women. Therefore, this study investigated BFR-induced alterations in pressor response and systemic flow redistribution at rest during two commonly used pressures (50% and 80% limb occlusion pressure [LOP]). Fifteen women (22.1 ± 4.2 years) completed two randomised sessions involving 8-min of bilateral, lower limb restriction at 50% or 80% LOP followed by 8-min of recovery post-deflation. Changes in vascular (arterial diameter [DIA], time-averaged mean velocity [TAMV], volume flow [VF], and area) and hemodynamic (heart rate [HR] and blood pressure) measures over time (pre-, during, post-occlusion) and by session (50% vs. 80% LOP) were tested using repeated measures analysis of variance. Repeated measures correlations (rrm) quantified common intraindividual associations between BFR-induced hemodynamic and vascular responses. HR increased from baseline during 50% LOP and remained elevated during recovery (p < 0.05). HR increased from baseline during 80% LOP, while tibial VF and TAMV decreased (p < 0.03 for all). HR and TAMV values returned to baseline during recovery, while brachial artery VF decreased (p < 0.05). Changes in HR, brachial VF, and brachial TAMV were similar between 50% and 80% LOP (rrm = 0.32–0.70, p < 0.05 for all). At 80% LOP, changes in HR were positively correlated with brachial VF (rrm = 0.38) and TAMV (rrm = 0.43) and negatively correlated with tibial VF (rrm = −0.36) and TAMV (rrm = −0.30) (p < 0.05 for all). Results suggest that BFR at 80% LOP elicits an acute systemic pressor reflex without concomitant increases in brachial arterial flow, while 50% LOP elicits a subdued response.

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来源期刊
CiteScore
3.40
自引率
5.60%
发文量
62
审稿时长
6-12 weeks
期刊介绍: Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest. Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.
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