精神病患者的美好生活:随访 10 年的首发精神病患者的积极成果率。

IF 5.9 2区 医学 Q1 PSYCHIATRY
Psychological Medicine Pub Date : 2024-07-01 Epub Date: 2024-02-23 DOI:10.1017/S0033291724000205
Carmen Simonsen, Gina Åsbø, Mike Slade, Kristin Fjelnseth Wold, Line Widing, Camilla Bärthel Flaaten, Magnus Johan Engen, Siv Hege Lyngstad, Erlend Gardsjord, Thomas Bjella, Kristin Lie Romm, Torill Ueland, Ingrid Melle
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引用次数: 0

摘要

背景:我们需要更多地了解首发精神病患者(FEP)的积极疗效。一项为期10年的FEP随访研究调查了全部样本以及双相情感谱系障碍(BD)和精神分裂症谱系障碍(SZ)精神病患者的个人康复率、情感健康和临床康复情况,以及这些积极结果的重叠情况:方法:在 10 年的随访中,通过结构化临床访谈对 FEP 参与者(n = 128)进行了重新评估。个人康复情况由 "康复过程问卷 "的 15 个项目进行自评(总分 ⩾45)。情绪健康状况由生活满意度量表(得分⩾5)和快乐时空体验量表(总分⩾72)进行自评。临床康复是指临床医生评定的症状缓解和功能正常(持续时间至少 1 年):在 FEP 中,个人康复率(50.8%)、生活满意度(60.9%)和愉悦感(57.5%)均高于临床康复率(33.6%)。尽管 SZ 的临床康复率低于 BD,但他们的个人康复率和情绪健康率却相当。个人康复与情绪健康的重叠率高于临床康复(χ2)。根据积极结果的组合,每位参与者都被分配到八个可能的结果组中的一个。这八个组别合并为三个同等规模的主要结果组别:33.6%临床康复并伴有个人康复和/或情绪健康;34.4%仅有个人康复和/或情绪健康;32.0%无:68%的患者在 10 年后至少有一项积极的结果,这表明他们在患有精神病后生活得很好。我们必须分享这一知识,为患者带来希望,并强调必须对主观和客观的积极结果进行评估,并在治疗中将其作为目标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A good life with psychosis: rate of positive outcomes in first-episode psychosis at 10-year follow-up.

Background: More knowledge about positive outcomes for people with first-episode psychosis (FEP) is needed. An FEP 10-year follow-up study investigated the rate of personal recovery, emotional wellbeing, and clinical recovery in the total sample and between psychotic bipolar spectrum disorders (BD) and schizophrenia spectrum disorders (SZ); and how these positive outcomes overlap.

Methods: FEP participants (n = 128) were re-assessed with structured clinical interviews at 10-year follow-up. Personal recovery was self-rated with the Questionnaire about the Process of Recovery-15-item scale (total score ⩾45). Emotional wellbeing was self-rated with the Life Satisfaction Scale (score ⩾5) and the Temporal Experience of Pleasure Scale (total score ⩾72). Clinical recovery was clinician-rated symptom-remission and adequate functioning (duration minimum 1 year).

Results: In FEP, rates of personal recovery (50.8%), life satisfaction (60.9%), and pleasure (57.5%) were higher than clinical recovery (33.6%). Despite lower rates of clinical recovery in SZ compared to BD, they had equal rates of personal recovery and emotional wellbeing. Personal recovery overlapped more with emotional wellbeing than with clinical recovery (χ2). Each participant was assigned to one of eight possible outcome groups depending on the combination of positive outcomes fulfilled. The eight groups collapsed into three equal-sized main outcome groups: 33.6% clinical recovery with personal recovery and/or emotional wellbeing; 34.4% personal recovery and/or emotional wellbeing only; and 32.0% none.

Conclusions: In FEP, 68% had minimum one positive outcome after 10 years, suggesting a good life with psychosis. This knowledge must be shared to instill hope and underlines that subjective and objective positive outcomes must be assessed and targeted in treatment.

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来源期刊
Psychological Medicine
Psychological Medicine 医学-精神病学
CiteScore
11.30
自引率
4.30%
发文量
711
审稿时长
3-6 weeks
期刊介绍: Now in its fifth decade of publication, Psychological Medicine is a leading international journal in the fields of psychiatry, related aspects of psychology and basic sciences. From 2014, there are 16 issues a year, each featuring original articles reporting key research being undertaken worldwide, together with shorter editorials by distinguished scholars and an important book review section. The journal''s success is clearly demonstrated by a consistently high impact factor.
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