José António Ferraz-Gonçalves, Adelaide Alves, Álvaro José Silva, Ana Carmo Valente, Ana Pina, Áurea Lima, Daniela Antunes, Francisco Cubal, Isabel Costa, Jorge Rodrigues, Mariana Costa, Mariana Ramos, Michael Luis, Sofia Garcês Soares, Sofia Sousa, Teresa Dias Moreira, Vânia Sá-Araújo, Maria José Bento
{"title":"与接受姑息治疗的癌症患者长期生存相关的因素:一项探索性研究","authors":"José António Ferraz-Gonçalves, Adelaide Alves, Álvaro José Silva, Ana Carmo Valente, Ana Pina, Áurea Lima, Daniela Antunes, Francisco Cubal, Isabel Costa, Jorge Rodrigues, Mariana Costa, Mariana Ramos, Michael Luis, Sofia Garcês Soares, Sofia Sousa, Teresa Dias Moreira, Vânia Sá-Araújo, Maria José Bento","doi":"10.1177/08258597241231005","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective:</b> Some patients with cancer admitted to palliative care have relatively long survivals of 1 year or more. The objective of this study was to find out factors associated with prolonged survival. <b>Methods:</b> Retrospective case-control study comparing the available data of patients with cancer who survived more than 1 year after admission in a palliative care service with patients with cancer who survived 6 months or less. The intended proportion was 4 controls for each case. Patients were identified through electronic records from 2012 until 2018. <b>Results:</b> And 1721 patients were identified. Of those patients, 111 (6.4%) survived for at least 1 year, and 363 (21.1%) were included as controls according to the established criteria. The intended proportion could not be reached; the proportion was only 3.3:1. The median survival of cases was 581 days (range: 371-2763), and the median survival of controls was 57 days (range: 1-182). In the multivariable analysis, patients with a hemoglobin ≥ 10.6 g/dL and a creatinine level >95 µmol/L had a higher probability of living more than 1 year. In contrast, patients with abnormal cognition, pain, anorexia, liver metastases, an Eastern Cooperative Oncology Group performance status >1, and a neutrophil/lymphocyte ratio ≥ 3.43 had a low probability of living more than 1 year. <b>Conclusion:</b> Several factors were statistically associated positively or negatively with prolonged survival. However, the data of this study should be confirmed in other studies.</p>","PeriodicalId":51096,"journal":{"name":"Journal of Palliative Care","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097604/pdf/","citationCount":"0","resultStr":"{\"title\":\"Factors Associated With Long Survival in Patients With Cancer Admitted to Palliative Care: An Exploratory Study.\",\"authors\":\"José António Ferraz-Gonçalves, Adelaide Alves, Álvaro José Silva, Ana Carmo Valente, Ana Pina, Áurea Lima, Daniela Antunes, Francisco Cubal, Isabel Costa, Jorge Rodrigues, Mariana Costa, Mariana Ramos, Michael Luis, Sofia Garcês Soares, Sofia Sousa, Teresa Dias Moreira, Vânia Sá-Araújo, Maria José Bento\",\"doi\":\"10.1177/08258597241231005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective:</b> Some patients with cancer admitted to palliative care have relatively long survivals of 1 year or more. The objective of this study was to find out factors associated with prolonged survival. <b>Methods:</b> Retrospective case-control study comparing the available data of patients with cancer who survived more than 1 year after admission in a palliative care service with patients with cancer who survived 6 months or less. The intended proportion was 4 controls for each case. Patients were identified through electronic records from 2012 until 2018. <b>Results:</b> And 1721 patients were identified. Of those patients, 111 (6.4%) survived for at least 1 year, and 363 (21.1%) were included as controls according to the established criteria. The intended proportion could not be reached; the proportion was only 3.3:1. The median survival of cases was 581 days (range: 371-2763), and the median survival of controls was 57 days (range: 1-182). In the multivariable analysis, patients with a hemoglobin ≥ 10.6 g/dL and a creatinine level >95 µmol/L had a higher probability of living more than 1 year. In contrast, patients with abnormal cognition, pain, anorexia, liver metastases, an Eastern Cooperative Oncology Group performance status >1, and a neutrophil/lymphocyte ratio ≥ 3.43 had a low probability of living more than 1 year. <b>Conclusion:</b> Several factors were statistically associated positively or negatively with prolonged survival. However, the data of this study should be confirmed in other studies.</p>\",\"PeriodicalId\":51096,\"journal\":{\"name\":\"Journal of Palliative Care\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097604/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Palliative Care\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/08258597241231005\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/2/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q4\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Palliative Care","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/08258597241231005","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
Factors Associated With Long Survival in Patients With Cancer Admitted to Palliative Care: An Exploratory Study.
Objective: Some patients with cancer admitted to palliative care have relatively long survivals of 1 year or more. The objective of this study was to find out factors associated with prolonged survival. Methods: Retrospective case-control study comparing the available data of patients with cancer who survived more than 1 year after admission in a palliative care service with patients with cancer who survived 6 months or less. The intended proportion was 4 controls for each case. Patients were identified through electronic records from 2012 until 2018. Results: And 1721 patients were identified. Of those patients, 111 (6.4%) survived for at least 1 year, and 363 (21.1%) were included as controls according to the established criteria. The intended proportion could not be reached; the proportion was only 3.3:1. The median survival of cases was 581 days (range: 371-2763), and the median survival of controls was 57 days (range: 1-182). In the multivariable analysis, patients with a hemoglobin ≥ 10.6 g/dL and a creatinine level >95 µmol/L had a higher probability of living more than 1 year. In contrast, patients with abnormal cognition, pain, anorexia, liver metastases, an Eastern Cooperative Oncology Group performance status >1, and a neutrophil/lymphocyte ratio ≥ 3.43 had a low probability of living more than 1 year. Conclusion: Several factors were statistically associated positively or negatively with prolonged survival. However, the data of this study should be confirmed in other studies.
期刊介绍:
The Journal of Palliative Care is a quarterly, peer-reviewed, international and interdisciplinary forum for practical, critical thought on palliative care and palliative medicine. JPC publishes high-quality original research, opinion papers/commentaries, narrative and humanities works, case reports/case series, and reports on international activities and comparative palliative care.