Gayathri Jagadish, M. Archana, K. S. Nataraj, Sandeep Desai, Vishnu Kurpad
{"title":"肝脏和骨髓中的隐性淀粉样变性","authors":"Gayathri Jagadish, M. Archana, K. S. Nataraj, Sandeep Desai, Vishnu Kurpad","doi":"10.25259/jhas_45_2023","DOIUrl":null,"url":null,"abstract":"Primary amyloidosis and multiple myeloma (MM) involve clonal plasma cell proliferation. Approximately 10–15% of patients with amyloidosis have MM. Characteristic apple-green birefringence using Congo red staining on polarized microscopy confirms amyloid. MM is prevalent at ages from 60 to 70 years. Amyloidosis commonly affects the heart, kidneys, gastrointestinal tract/liver and peripheral or autonomic nervous system predicting a poor prognosis due to organ deterioration. This case highlights the importance of diagnosing amyloidosis in a 60-year-old female where plasma cells were present in the liver and bone marrow along with amyloid deposits and for early initiation of intense chemotherapy.","PeriodicalId":499735,"journal":{"name":"Journal of Hematology and Allied Sciences","volume":"35 2","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Hidden amyloidosis in liver and bone marrow\",\"authors\":\"Gayathri Jagadish, M. Archana, K. S. Nataraj, Sandeep Desai, Vishnu Kurpad\",\"doi\":\"10.25259/jhas_45_2023\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Primary amyloidosis and multiple myeloma (MM) involve clonal plasma cell proliferation. Approximately 10–15% of patients with amyloidosis have MM. Characteristic apple-green birefringence using Congo red staining on polarized microscopy confirms amyloid. MM is prevalent at ages from 60 to 70 years. Amyloidosis commonly affects the heart, kidneys, gastrointestinal tract/liver and peripheral or autonomic nervous system predicting a poor prognosis due to organ deterioration. This case highlights the importance of diagnosing amyloidosis in a 60-year-old female where plasma cells were present in the liver and bone marrow along with amyloid deposits and for early initiation of intense chemotherapy.\",\"PeriodicalId\":499735,\"journal\":{\"name\":\"Journal of Hematology and Allied Sciences\",\"volume\":\"35 2\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hematology and Allied Sciences\",\"FirstCategoryId\":\"0\",\"ListUrlMain\":\"https://doi.org/10.25259/jhas_45_2023\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hematology and Allied Sciences","FirstCategoryId":"0","ListUrlMain":"https://doi.org/10.25259/jhas_45_2023","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Primary amyloidosis and multiple myeloma (MM) involve clonal plasma cell proliferation. Approximately 10–15% of patients with amyloidosis have MM. Characteristic apple-green birefringence using Congo red staining on polarized microscopy confirms amyloid. MM is prevalent at ages from 60 to 70 years. Amyloidosis commonly affects the heart, kidneys, gastrointestinal tract/liver and peripheral or autonomic nervous system predicting a poor prognosis due to organ deterioration. This case highlights the importance of diagnosing amyloidosis in a 60-year-old female where plasma cells were present in the liver and bone marrow along with amyloid deposits and for early initiation of intense chemotherapy.
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