侵袭性念珠菌病引发糖尿病酮症酸中毒

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摘要

糖尿病酮症酸中毒(DKA)是一种常见但致命的糖尿病并发症,其特征是不受控制的高血糖、代谢性酸中毒和体内酮体浓度升高。这种可预防的高血糖急症每年导致超过 50,000 个住院日[1]。感染、不遵医嘱用药是诱发 DKA 的主要因素,但心肌梗死、中风、外伤和药物滥用也可能导致 DKA。DKA 的临床特征包括恶心、呕吐、脱水、腹部疼痛、库斯莫呼吸模式甚至精神感觉改变。不同类型的感染可诱发 DKA,常见的有肺炎、尿路感染、口腔粘膜感染和耳部感染。本病例报告旨在回顾有关 DKA 诱发因素的知识缺口。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Invasive Candidiasis Causing Diabetic Ketoacidosis
Diabetic ketoacidosis (DKA) is a common yet fatal complication of diabetes mellitus which is characterised by uncontrolled hyperglycaemia, metabolic acidosis, and increased body ketone concentration. This preventable hyperglycaemic emergency accounts for more than 50,000 hospital days per year [1]. Infections, non-compliance to medication are the main precipitating factors for DKA, although myocardial infarction, stroke, trauma, and substance abuse may result in DKA. Clinical features of the same include nausea, vomiting, dehydration, pain abdomen, Kussmaul breathing pattern or even altered mental sensorium. Different types of infections can precipitate DKA, commonly of which are pneumonia, urinary tract infection, Oro-mucosal and aural infections. Careful evaluation and identification of precipitating factor should be made earlier for prompt treatment The aim of this case report is to review knowledge gaps in precipitating factors of DKA.
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