对中风幸存者进行基于口语的自动认知评估

Bahman Mirheidari , Simon M. Bell , Kirsty Harkness , Daniel Blackburn , Heidi Christensen
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引用次数: 0

摘要

脑卒中幸存者(SSs)在首次脑卒中后往往会出现认知能力下降,因此需要重复进行脑卒中后认知评估。目前的评估方法,如基于纸笔的蒙特利尔认知评估(MoCA),非常耗时,而且往往需要与熟练的临床医生面对面交流。而此时患者的康复需求往往多种多样。为了应对这些挑战,我们的论文介绍了首个用于该群体的同类系统。CognoSpeak 是一种自动认知评估系统,患者可以在中风后立即在病房使用(基线),随后在家中使用(随访)。CognoSpeak 通过要求用户与虚拟代理互动,回答问题并完成临床任务和认知测试来评估认知能力的下降。然后,该系统利用人工智能来提取和处理语音、语言和互动线索,以了解认知能力衰退的情况。该系统最初是为痴呆症开发的;在此,我们展示了它可以成功预测 MoCA 分数(回归),并根据基于 MoCA 的阈值识别中风幸存者队列中的认知衰退(分类)。我们探索了大量基于声音和文本的特征以及不同的机器学习模型。利用由 55 个 SS CognoSpeak 互动组成的独特数据集,我们的研究结果表明,回归和分类预测的性能都非常出色,最佳回归结果(归一化均方根误差 (N-RMSE) )为 0.092。此外,我们还表明,使用逻辑回归分类器对 MoCA 26 分临界值进行直接分类可获得 0.74 的 F1 分数(特异性:0.73,灵敏度:0.75)。这首次证明了该系统的鲁棒性和临床潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Spoken language-based automatic cognitive assessment of stroke survivors

Stroke survivors (SSs) often experience cognitive decline following their initial stroke, necessitating repeat post-stroke cognitive assessments. Current methods of assessment, such as the pen-and-paper-based Montreal Cognitive Assessment (MoCA), is time-consuming and often reliant on seeing skilled clinicians in person. This is at a time when patients have a lot of often diverse rehabilitation needs. To address these challenges, our paper introduces the first system of its kind to be used for this cohort. CognoSpeak is an automated cognitive assessment system that people can use initially on the ward immediately post-stroke (baseline) and subsequently at home (follow-ups). CognoSpeak assesses cognitive decline by asking users to engage with a virtual agent by answering questions and completing clinically-motivated tasks and cognitive tests. The system then uses AI to extract and process speech, language, and interactional cues for cognitive decline. The system was originally developed for dementia; here, we show that it can successfully predict MoCA scores (regression) and identify cognitive decline predicated on a MoCA-based threshold (classification) in the stroke survivor cohort. We explore an extensive set of acoustic- and text-based features as well as different machine learning models. Leveraging a unique dataset of 55 SS CognoSpeak interactions, our findings show excellent performance for both regression and classification style prediction with the best regression result (Normalised Root Mean Squared Error (N-RMSE)) of 0.092. In addition, we show that direct classification of the MoCA score cutoff of 26 yields an F1-score of 0.74 (Specificity: 0.73, Sensitivity: 0.75) using a Logistic Regression Classifier. This demonstrates the first evidence of the system’s robustness and clinical potential.

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