体重指数和性别及其对软骨修复术后患者报告结果的影响:ICRS患者登记的启示

Gwenllian F. Tawy , Reza Ojaghi , Michael J. McNicholas
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引用次数: 0

摘要

导言:在多达 60% 的关节镜检查中都会发现膝关节软骨损伤,无论是单独损伤还是伴有其他损伤。尽管目前的研究发现,体重指数(BMI)为 30 kg/m2 的患者接受软骨修复术后会出现不良后果,但我们对所有体重指数类别的患者术前体重指数与术后患者报告结果之间的关系仍缺乏了解。研究目的:本研究旨在通过国际软骨再生与关节保存协会(ICRS)患者登记处探索这种关系,同时考虑到性别差异。重点结果是膝骨关节炎结果评分(KOOS)和 EQ-5D 评分。结果 在提取数据时,登记在册的 3194 名患者中有 1757 人接受了手术治疗,其中 336 人在术后 6 周、6 个月和 1 年有完整的 KOOS 或 EQ-5D 评分。分析表明,无论是男性(平均 BMI - 28.2 kg/m2)还是女性(平均 BMI - 25.3 kg/m2),其数据集均未显示 BMI 与患者报告的结果之间存在相关性。虽然超重分级的体重指数与正常分级的体重指数相比与较差的预后无关,但目前的文献仍然支持体重指数为 30 kg/m2 与软骨修复不良和失败有关的观点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Body mass index and sex and their effect on patient-reported outcomes following cartilage repair: an insight from the International Cartilage Regeneration and Joint Preservation Society Patient Registry

Introduction

Chondral injuries in the knee, whether isolated or accompanying other injuries are found in as many as 60% of arthroscopic examinations. Although current research has identified negative outcomes for patients with a body mass index (BMI) >30 kg/m2 undergoing chondral repair, our understanding of the relationship between presurgery BMI and postoperative patient-reported outcomes across all BMI categories remains lacking.

Objectives

Through the International Cartilage Regeneration and Joint Preservation Society (ICRS) Patient Registry, this study aimed to explore this relationship, taking into account sex variations.

Methods

The ICRS Patient Registry was used to extract the data for this study. The outcomes in focus were the Knee Osteoarthritis Outcome Score (KOOS) and EQ-5D scores. Pearson and Spearman correlation methods were applied and the level of significance was set as α = 0.05.

Results

Of 3194 Registry patients at the time of data extraction, 1757 had undergone a surgical procedure, and 336 of these had complete KOOS or EQ-5D scores available for 6-week, 6-month, and 1-year postoperation. Analyses revealed that neither male (average BMI – 28.2 kg/m2) nor female (average BMI – 25.3 kg/m2) data sets indicated a correlation between BMI and the patient-reported outcomes.

Conclusions

BMI, irrespective of sex, is not correlated with patient-reported outcomes in patients enrolled in the ICRS Registry with a BMI <30 kg/m2. Although BMIs in the overweight classification were not associated with poorer outcomes than BMIs in the normal classification, the current literature continues to support the notion that a BMI >30 kg/m2 is linked to poor cartilage repair and failure.

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