Asif Naeem, Z. N. Qaisrani, Shazia, A. Noor, Imran Hussain, Asif Raheem
{"title":"纳米粒子的给药途径,以对抗耐药细菌。","authors":"Asif Naeem, Z. N. Qaisrani, Shazia, A. Noor, Imran Hussain, Asif Raheem","doi":"10.34016/pjbt.2024.21.01.861","DOIUrl":null,"url":null,"abstract":"In the middle of the late century, the concept of medicine has been reshaped and reformed by the discovery of antibiotics. Untreatable infectious diseases have become treatable, However, with time microbes adapt to resist the antibiotic treatments due to their enormous adaptive ability. Therefore, new antibiotics were required to combat these resistant bacteria. But the enormous adaptive ability of bacteria has turned the next generation of antibiotics obsolete. Thus, Nanoparticles play a crucial role due to their antibacterial activity. Besides, these can act as carriers for various antibiotics to increase their efficiency against superbugs. The current review provides an in-depth overview of nanoparticles, their biosynthesis, antibacterial activity, and synergistic effects with various antibiotics.","PeriodicalId":411068,"journal":{"name":"Pakistan Journal of Biotechnology","volume":" 44","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ROUTE OF ADMINISTRATION OF NANOPARTICLES COMBATING A RESISTANT BACTERIUM.\",\"authors\":\"Asif Naeem, Z. N. Qaisrani, Shazia, A. Noor, Imran Hussain, Asif Raheem\",\"doi\":\"10.34016/pjbt.2024.21.01.861\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In the middle of the late century, the concept of medicine has been reshaped and reformed by the discovery of antibiotics. Untreatable infectious diseases have become treatable, However, with time microbes adapt to resist the antibiotic treatments due to their enormous adaptive ability. Therefore, new antibiotics were required to combat these resistant bacteria. But the enormous adaptive ability of bacteria has turned the next generation of antibiotics obsolete. Thus, Nanoparticles play a crucial role due to their antibacterial activity. Besides, these can act as carriers for various antibiotics to increase their efficiency against superbugs. The current review provides an in-depth overview of nanoparticles, their biosynthesis, antibacterial activity, and synergistic effects with various antibiotics.\",\"PeriodicalId\":411068,\"journal\":{\"name\":\"Pakistan Journal of Biotechnology\",\"volume\":\" 44\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-10\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pakistan Journal of Biotechnology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.34016/pjbt.2024.21.01.861\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pakistan Journal of Biotechnology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.34016/pjbt.2024.21.01.861","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ROUTE OF ADMINISTRATION OF NANOPARTICLES COMBATING A RESISTANT BACTERIUM.
In the middle of the late century, the concept of medicine has been reshaped and reformed by the discovery of antibiotics. Untreatable infectious diseases have become treatable, However, with time microbes adapt to resist the antibiotic treatments due to their enormous adaptive ability. Therefore, new antibiotics were required to combat these resistant bacteria. But the enormous adaptive ability of bacteria has turned the next generation of antibiotics obsolete. Thus, Nanoparticles play a crucial role due to their antibacterial activity. Besides, these can act as carriers for various antibiotics to increase their efficiency against superbugs. The current review provides an in-depth overview of nanoparticles, their biosynthesis, antibacterial activity, and synergistic effects with various antibiotics.