对播散性组织胞浆菌病的诊断见解：一份突出骨髓分析的病例报告

IF 1.3 Q4 MICROBIOLOGY

Iranian Journal of Microbiology Pub Date : 2024-02-12 DOI:10.18502/ijm.v16i1.14886

Vaanya Kaushik, R. Khanna, V. Khanna, Muralidhar Varma

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引用次数: 0

摘要

印度卡纳塔克邦马尼帕尔市卡斯特尔巴医院临床实验室对一名 43 岁免疫力低下的女性患者进行了骨髓检查，确诊其患有播散性组织胞浆菌病。患者出现体重减轻、食欲减退和全血细胞减少等症状，接受了骨髓抽吸和活组织检查。骨髓检查发现了艾滋病毒相关变化和荚膜组织胞浆菌的酵母形式，证实了播散性组织胞浆菌病。报告强调，骨髓检查是一种诊断工具，对此类病例具有显著的敏感性。报告强调，鉴于组织胞浆菌病具有潜在的致命性，而且需要及时进行治疗干预以改善预后，因此免疫力低下的患者必须认识到组织胞浆菌病并及早进行诊断。

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Diagnostic insights into disseminated histoplasmosis: a case report highlighting bone marrow analysis

We present a case of a 43-year-old immunocompromised female patient diagnosed with disseminated histoplasmosis on bone marrow examination, at clinical laboratory of Kasturba Hospital, Manipal, Karnataka, India. The patient, presenting with symptoms like weight loss, appetite loss, and pancytopenia, underwent bone marrow aspiration and biopsy. The bone marrow studies revealed HIV-associated changes and the yeast form of Histoplasma capsulatum, confirming disseminated histoplasmosis. Bone marrow examination is highlighted as a diagnostic tool with significant sensitivity in such cases. The report stresses on the importance of awareness and early diagnosis of histoplasmosis in immunocompromised patients, given its potential lethality and the need for timely therapeutic intervention for better prognosis.

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来源期刊

Iranian Journal of Microbiology MICROBIOLOGY-

CiteScore

2.40

自引率

7.10%

发文量

审稿时长

12 weeks

期刊介绍： The Iranian Journal of Microbiology (IJM) is an international, multi-disciplinary, peer-reviewed journal that provides rapid publication of the most advanced scientific research in the areas of basic and applied research on bacteria and other micro-organisms, including bacteria, viruses, yeasts, fungi, microalgae, and protozoa concerning the development of tools for diagnosis and disease control, epidemiology, antimicrobial agents, clinical microbiology, immunology, Genetics, Genomics and Molecular Biology. Contributions may be in the form of original research papers, review articles, short communications, case reports, technical reports, and letters to the Editor. Research findings must be novel and the original data must be available for review by the Editors, if necessary. Studies that are preliminary, of weak originality or merely descriptive as well as negative results are not appropriate for the journal. Papers considered for publication must be unpublished work (except in an abstract form) that is not under consideration for publication anywhere else, and all co-authors should have agreed to the submission. Manuscripts should be written in English.