K. P. Shinde, P. K. Chaturvedi, J. S. Oh, J. N. Park, K. Choi, D. Shin, J. Oh, S. Yi, K. Ku, S. Lee, C. H. Chung, Woo Yoon Park, Joon Sik Park
{"title":"Zr48Cu36Al9Ag7 非晶合金手术刀的制造和体外生物相容性评估","authors":"K. P. Shinde, P. K. Chaturvedi, J. S. Oh, J. N. Park, K. Choi, D. Shin, J. Oh, S. Yi, K. Ku, S. Lee, C. H. Chung, Woo Yoon Park, Joon Sik Park","doi":"10.1007/s12540-023-01622-4","DOIUrl":null,"url":null,"abstract":"<div><p>Zirconium based amorphous alloys are suitable for biomedical applications because of their excellent corrosion resistance and biocompatibility. In this study, Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous alloy was fabricated by arc melting and ingot converted into the plate-shaped amorphous alloy by the suction method in a water cooled copper mold. Scalpels of the amorphous alloy were fabricated by using the polishing method. The X-ray diffraction and differential scanning calorimetry confirmed the amorphous nature of the Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> alloy. Elemental confirmation of the amorphous alloy was confirmed with X-ray photoelectron spectroscopy analysis. The hardness of amorphous alloy was compared with a commercial stainless steel scalpel. The observed corrosion potentials of the stainless steel scalpel and Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous scalpel were − 0.6 V and − 0.4 V, respectively which confirms that the corrosion resistance of the amorphous alloy is better than stainless steel. The biomedical application of the Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous alloy scalpel is supported by a comparative study that examined in vitro cytotoxicity, cell viability, and wound healing tests and compared it with the standard stainless steel scalpel.</p><h3>Graphical Abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":703,"journal":{"name":"Metals and Materials International","volume":"30 7","pages":"1794 - 1804"},"PeriodicalIF":3.3000,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Fabrication and In Vitro Biocompatibility Evaluation of Zr48Cu36Al9Ag7 Amorphous Alloy Scalpel\",\"authors\":\"K. P. Shinde, P. K. Chaturvedi, J. S. Oh, J. N. Park, K. Choi, D. Shin, J. Oh, S. Yi, K. Ku, S. Lee, C. H. Chung, Woo Yoon Park, Joon Sik Park\",\"doi\":\"10.1007/s12540-023-01622-4\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Zirconium based amorphous alloys are suitable for biomedical applications because of their excellent corrosion resistance and biocompatibility. In this study, Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous alloy was fabricated by arc melting and ingot converted into the plate-shaped amorphous alloy by the suction method in a water cooled copper mold. Scalpels of the amorphous alloy were fabricated by using the polishing method. The X-ray diffraction and differential scanning calorimetry confirmed the amorphous nature of the Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> alloy. Elemental confirmation of the amorphous alloy was confirmed with X-ray photoelectron spectroscopy analysis. The hardness of amorphous alloy was compared with a commercial stainless steel scalpel. The observed corrosion potentials of the stainless steel scalpel and Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous scalpel were − 0.6 V and − 0.4 V, respectively which confirms that the corrosion resistance of the amorphous alloy is better than stainless steel. The biomedical application of the Zr<sub>48</sub>Cu<sub>36</sub>Al<sub>9</sub>Ag<sub>7</sub> amorphous alloy scalpel is supported by a comparative study that examined in vitro cytotoxicity, cell viability, and wound healing tests and compared it with the standard stainless steel scalpel.</p><h3>Graphical Abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":703,\"journal\":{\"name\":\"Metals and Materials International\",\"volume\":\"30 7\",\"pages\":\"1794 - 1804\"},\"PeriodicalIF\":3.3000,\"publicationDate\":\"2024-02-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Metals and Materials International\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s12540-023-01622-4\",\"RegionNum\":3,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MATERIALS SCIENCE, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Metals and Materials International","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s12540-023-01622-4","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
Fabrication and In Vitro Biocompatibility Evaluation of Zr48Cu36Al9Ag7 Amorphous Alloy Scalpel
Zirconium based amorphous alloys are suitable for biomedical applications because of their excellent corrosion resistance and biocompatibility. In this study, Zr48Cu36Al9Ag7 amorphous alloy was fabricated by arc melting and ingot converted into the plate-shaped amorphous alloy by the suction method in a water cooled copper mold. Scalpels of the amorphous alloy were fabricated by using the polishing method. The X-ray diffraction and differential scanning calorimetry confirmed the amorphous nature of the Zr48Cu36Al9Ag7 alloy. Elemental confirmation of the amorphous alloy was confirmed with X-ray photoelectron spectroscopy analysis. The hardness of amorphous alloy was compared with a commercial stainless steel scalpel. The observed corrosion potentials of the stainless steel scalpel and Zr48Cu36Al9Ag7 amorphous scalpel were − 0.6 V and − 0.4 V, respectively which confirms that the corrosion resistance of the amorphous alloy is better than stainless steel. The biomedical application of the Zr48Cu36Al9Ag7 amorphous alloy scalpel is supported by a comparative study that examined in vitro cytotoxicity, cell viability, and wound healing tests and compared it with the standard stainless steel scalpel.
期刊介绍：
Metals and Materials International publishes original papers and occasional critical reviews on all aspects of research and technology in materials engineering: physical metallurgy, materials science, and processing of metals and other materials. Emphasis is placed on those aspects of the science of materials that are concerned with the relationships among the processing, structure and properties (mechanical, chemical, electrical, electrochemical, magnetic and optical) of materials. Aspects of processing include the melting, casting, and fabrication with the thermodynamics, kinetics and modeling.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
