改善空气颗粒物对健康不利影响的天然产品

IF 2.5 4区 生物学 Q3 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Dongyup Hahn, Min Jeong Kim, Yun Kwon, Eunjeong Kim, Dong Ho Park, Jong-Sup Bae
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引用次数: 0

摘要

以颗粒物(PM)为媒介的空气污染对人类健康的威胁是现代社会的沉重负担。例如,可吸入颗粒物会吸入肺部或影响角质细胞,诱发活性氧,从而产生氧化应激、炎症反应和遗传毒性。天然产品是抗氧化和抗炎化学物质的丰富来源,可以抵消可吸入颗粒物在人体内的作用。本综述汇集了有关生物活性天然产品的知识,这些天然产品可改善由可吸入颗粒物引起的健康状况。根据生物合成来源或资源对天然产物进行了分类:酚类化合物(包括类黄酮和其他酚类化合物)、萜类化合物、类固醇、来自海洋藻类的植物化学物质、他汀类、脂类、生物碱和其他含氮天然产物。这篇综述文章介绍了用组织细胞或动物模型研究天然产品的结构和生物活性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Natural products ameliorating the adverse health effects by air particulate matter

Natural products ameliorating the adverse health effects by air particulate matter

The threats of air pollution mediated by particulate matter (PM) to human health are severe burdens to modern society. For example, PM is inhaled in the lungs or affects keratinocytes to induce reactive oxygen species that exert oxidative stress, inflammatory responses, and genotoxicity. Natural products are rich sources of the antioxidant and anti-inflammatory chemicals that might counteract what PM does in the human body. This review provides a compilation of knowledge on bioactive natural products that improve the health conditions from PM-induced health outcomes. The natural products were classified according to biosynthetic origins or resources: phenolic compounds including flavonoids and other phenolics, terpenoids, steroids, phytochemicals from marine algae, statins, lipids, alkaloids, and other nitrogen-containing natural products. This review article covers the structures and biological activity of natural products investigated with tissue cells or animal models.

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来源期刊
Biotechnology and Bioprocess Engineering
Biotechnology and Bioprocess Engineering 工程技术-生物工程与应用微生物
CiteScore
5.00
自引率
12.50%
发文量
79
审稿时长
3 months
期刊介绍: Biotechnology and Bioprocess Engineering is an international bimonthly journal published by the Korean Society for Biotechnology and Bioengineering. BBE is devoted to the advancement in science and technology in the wide area of biotechnology, bioengineering, and (bio)medical engineering. This includes but is not limited to applied molecular and cell biology, engineered biocatalysis and biotransformation, metabolic engineering and systems biology, bioseparation and bioprocess engineering, cell culture technology, environmental and food biotechnology, pharmaceutics and biopharmaceutics, biomaterials engineering, nanobiotechnology, and biosensor and bioelectronics.
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