按原籍身份划分的邻里特征差异和 10 年痴呆症风险。

IF 5.9 2区 医学 Q1 PSYCHIATRY
R Wong, D Soong
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引用次数: 0

摘要

目的:先前的研究表明,邻里关系不利会增加痴呆症风险。然而,关于祖籍与认知障碍之间的关系,目前尚无定论。据我们所知,我们的研究是第一项分析出生地和邻里如何相互作用影响痴呆症风险的研究:我们从 "全国健康与老龄化趋势研究"(National Health and Aging Trends Study)中获取了十年(2011-2020 年)的前瞻性队列数据。在应用抽样加权和缺失数据归因后,利用原籍身份(外国出生或本国出生)以及邻里关系混乱(垃圾、涂鸦和空缺)和社会凝聚力(相互了解、帮助和信任)的综合得分,对痴呆症诊断时间进行了考克斯回归分析:在代表 2,690 万老年人的加权样本中,约有 9.5%(n=250 万)的老年人在国外出生,24.4%(n=650 万)的老年人曾被诊断患有痴呆症。平均基线邻里身体失调率为 0.19(范围 0-9),基线社会凝聚力为 4.28(范围 0-6)。与本地出生的老年人(平均值 = 0.18)相比,外国出生的老年人(平均值 = 0.28)的邻里身体失调基线明显更高(t = -2.4,p = .02)。与本地出生的老年人(平均值 = 4.33)相比,外国出生的老年人(平均值 = 3.57)的基线邻里社会凝聚力明显较低(t = 5.5,p < .001)。在对社会人口学、健康和邻里变量进行调整后,外国出生的老年人患痴呆症的风险明显高出 51%(调整后危险比 = 1.51,95% CI = 1.19-1.90,p < .01)。出生地与邻里身体失调或社会凝聚力之间没有明显的交互作用:我们的研究结果表明,与本地出生的老年人相比,外国出生的老年人的邻里关系更混乱,社会凝聚力更低。尽管我们观察到外国出生的老年人患痴呆症的风险较高,但这种关系并没有被邻里关系混乱或社会凝聚力所调节。要了解是哪些因素导致外国出生的老年人患痴呆症的风险升高,还需要进一步的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Disparities in neighbourhood characteristics and 10-year dementia risk by nativity status.

Aims: Prior research indicates that neighbourhood disadvantage increases dementia risk. There is, however, inconclusive evidence on the relationship between nativity and cognitive impairment. To our knowledge, our study is the first to analyse how nativity and neighbourhood interact to influence dementia risk.

Methods: Ten years of prospective cohort data (2011-2020) were retrieved from the National Health and Aging Trends Study, a nationally representative sample of 5,362 U.S. older adults aged 65+. Cox regression analysed time to dementia diagnosis using nativity status (foreign- or native-born) and composite scores for neighbourhood physical disorder (litter, graffiti and vacancies) and social cohesion (know, help and trust each other), after applying sampling weights and imputing missing data.

Results: In a weighted sample representing 26.9 million older adults, about 9.5% (n = 2.5 million) identified as foreign-born and 24.4% (n = 6.5 million) had an incident dementia diagnosis. Average baseline neighbourhood physical disorder was 0.19 (range 0-9), and baseline social cohesion was 4.28 (range 0-6). Baseline neighbourhood physical disorder was significantly higher among foreign-born (mean = 0.28) compared to native-born (mean = 0.18) older adults (t = -2.4, p = .02). Baseline neighbourhood social cohesion was significantly lower for foreign-born (mean = 3.57) compared to native-born (mean = 4.33) older adults (t = 5.5, p < .001). After adjusting for sociodemographic, health and neighbourhood variables, foreign-born older adults had a 51% significantly higher dementia risk (adjusted hazard ratio = 1.51, 95% CI = 1.19-1.90, p < .01). There were no significant interactions for nativity with neighbourhood physical disorder or social cohesion.

Conclusions: Our findings suggest that foreign-born older adults have higher neighbourhood physical disorder and lower social cohesion compared to native-born older adults. Despite the higher dementia risk, we observed for foreign-born older adults, and this relationship was not moderated by either neighbourhood physical disorder or social cohesion. Further research is needed to understand what factors are contributing to elevated dementia risk among foreign-born older adults.

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来源期刊
CiteScore
7.80
自引率
1.20%
发文量
121
审稿时长
>12 weeks
期刊介绍: Epidemiology and Psychiatric Sciences is a prestigious international, peer-reviewed journal that has been publishing in Open Access format since 2020. Formerly known as Epidemiologia e Psichiatria Sociale and established in 1992 by Michele Tansella, the journal prioritizes highly relevant and innovative research articles and systematic reviews in the areas of public mental health and policy, mental health services and system research, as well as epidemiological and social psychiatry. Join us in advancing knowledge and understanding in these critical fields.
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