韩国单中心回顾性队列:采用夹切内镜全层切除术的胃肠道间质瘤内镜切除术。

IF 2.1 Q3 GASTROENTEROLOGY & HEPATOLOGY
Clinical Endoscopy Pub Date : 2024-05-01 Epub Date: 2024-02-15 DOI:10.5946/ce.2023.144
Yuri Kim, Ji Yong Ahn, Hwoon-Yong Jung, Seokin Kang, Ho June Song, Kee Don Choi, Do Hoon Kim, Jeong Hoon Lee, Hee Kyong Na, Young Soo Park
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引用次数: 0

摘要

背景/目的:为了克服传统内镜下胃肠道间质瘤(GISTs)切除术的技术局限性,已经开发出了多种方法。在这项研究中,我们考察了夹切手术(夹切内镜全厚切除术 [cc-EFTR])在胃部 GIST 中的作用和可行性:方法:回顾性研究了2005年至2021年间83例经内镜切除术确诊的胃腺体瘤患者的病历。此外,还分析了临床特征和结果:结果:分别有51名和32名患者接受了内镜粘膜下剥离术(ESD)和cc-EFTR。ESD组(52.9%)和cc-EFTR组(90.6%)的GIST均在胃的上三分之一处被发现。在cc-EFTR组中,大多数GIST位于深层固有肌或浆膜层,占96.9%,而ESD组为45.1%。ESD组和cc-EFTR组的R0切除率分别为51.0%和84.4%。由于肿瘤残留(5 例)和术后不良反应(2 例),7 例(8.4%)患者需要接受手术治疗(6 例患者接受了ESD,1 例患者接受了cc-EFTR)。除ESD组的一名患者外,接受R0或R1切除术的患者在中位14个月的随访期间均出现复发:结论:Cc-EFTR显示了较高的R0切除率,因为该手术安全、成功地切除了小胃肠GIST。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Endoscopic resection of gastric gastrointestinal stromal tumor using clip-and-cut endoscopic full-thickness resection: a single-center, retrospective cohort in Korea.

Background/aims: To overcome the technical limitations of classic endoscopic resection for gastric gastrointestinal stromal tumors (GISTs), various methods have been developed. In this study, we examined the role and feasibility of clip-and-cut procedures (clip-and-cut endoscopic full-thickness resection [cc-EFTR]) for gastric GISTs.

Methods: Medical records of 83 patients diagnosed with GISTs after endoscopic resection between 2005 and 2021 were retrospectively reviewed. Moreover, clinical characteristics and outcomes were analyzed.

Results: Endoscopic submucosal dissection (ESD) and cc-EFTR were performed in 51 and 32 patients, respectively. The GISTs were detected in the upper third of the stomach for ESD (52.9%) and cc-EFTR (90.6%). Within the cc-EFTR group, a majority of GISTs were located in the deep muscularis propria or serosal layer, accounting for 96.9%, as opposed to those in the ESD group (45.1%). The R0 resection rates were 51.0% and 84.4% in the ESD and cc-EFTR groups, respectively. Seven (8.4%) patients required surgical treatment (six patients underwent ESD and one underwent cc-EFTR,) due to residual tumor (n=5) and post-procedure adverse events (n=2). Patients undergoing R0 or R1 resection did not experience recurrence during a median 14-month follow-up period, except for one patient in the ESD group.

Conclusions: cc-EFTR displayed a high R0 resection rate; therefore, it is a safe and effective therapeutic option for small gastric GISTs.

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来源期刊
Clinical Endoscopy
Clinical Endoscopy GASTROENTEROLOGY & HEPATOLOGY-
CiteScore
4.40
自引率
8.00%
发文量
95
审稿时长
26 weeks
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