Karla Monterrubio-Gómez, Nathan Constantine-Cooke, Catalina A. Vallejos
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引用次数: 0
摘要
在对竞争风险(CR)生存数据建模时,统计和机器学习文献中都提出了几种技术。最先进的方法对经典方法进行了扩展,采用了更灵活的假设,可以提高预测性能,允许高维数据和缺失值等。尽管如此,现代方法尚未在应用环境中得到广泛应用。本文旨在通过提供一份简明的 CR 生存方法简编,对各种方法进行统一的符号和解释,从而帮助这些方法的应用。我们重点介绍了可用的软件,并在可能的情况下通过可重现的 R 小节演示了这些软件的用法。此外,我们还讨论了在这种情况下可能影响基准研究的两个主要问题:性能指标的选择和可重复性。
A review on statistical and machine learning competing risks methods
When modeling competing risks (CR) survival data, several techniques have been proposed in both the statistical and machine learning literature. State-of-the-art methods have extended classical approaches with more flexible assumptions that can improve predictive performance, allow high-dimensional data and missing values, among others. Despite this, modern approaches have not been widely employed in applied settings. This article aims to aid the uptake of such methods by providing a condensed compendium of CR survival methods with a unified notation and interpretation across approaches. We highlight available software and, when possible, demonstrate their usage via reproducible R vignettes. Moreover, we discuss two major concerns that can affect benchmark studies in this context: the choice of performance metrics and reproducibility.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.