气管脱细胞的当前策略:系统回顾

IF 3 Q3 MATERIALS SCIENCE, BIOMATERIALS
International Journal of Biomaterials Pub Date : 2024-02-06 eCollection Date: 2024-01-01 DOI:10.1155/2024/3355239
Dhihintia Jiwangga, Ferdiansyah Mahyudin, Gondo Mastutik, Juliana, Estya Nadya Meitavany
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引用次数: 0

摘要

脱细胞过程对于制作缺失气管段的替代物至关重要,而药剂和方法的选择对结果有很大影响。本文旨在利用PRISMA流程图系统回顾各种气管脱细胞制剂和方法的疗效。纳入标准包括 2018 年至 2023 年间发表的实验研究,以英文撰写,详细介绍了与组织病理学解剖、DNA 定量、ECM 评估和生物力学特征相关的结果。排除标准包括与 3D 打印、生物材料和部分脱细胞相关的研究。通过在 PubMed、NCBI 和 ScienceDirect 上进行全面搜索,共获得 17 篇相关文献。在气管脱细胞的过程中,各种药剂和方法的整合被证明是有效的,同时也突出了每种药剂和方法的明显优势和缺点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Strategies for Tracheal Decellularization: A Systematic Review.

The process of decellularization is crucial for producing a substitute for the absent tracheal segment, and the choice of agents and methods significantly influences the outcomes. This paper aims to systematically review the efficacy of diverse tracheal decellularization agents and methods using the PRISMA flowchart. Inclusion criteria encompassed experimental studies published between 2018 and 2023, written in English, and detailing outcomes related to histopathological anatomy, DNA quantification, ECM evaluation, and biomechanical characteristics. Exclusion criteria involved studies related to 3D printing, biomaterials, and partial decellularization. A comprehensive search on PubMed, NCBI, and ScienceDirect yielded 17 relevant literatures. The integration of various agents and methods has proven effective in the process of tracheal decellularization, highlighting the distinct advantages and drawbacks associated with each agent and method.

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来源期刊
International Journal of Biomaterials
International Journal of Biomaterials MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
4.30
自引率
3.20%
发文量
50
审稿时长
21 weeks
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