我们对符合条件的器官捐献者了解多少?对地方登记处数据的分析。

IF 2.1 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Michał Kisiołek, Bartosz Blada, Jędrzej Hyla, Jakub Sikora, Zbigniew Putowski, Łukasz Krzych, Wojciech Saucha
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引用次数: 0

摘要

背景:器官捐献供需失衡仍是国际辩论的热门话题。在波兰,脑死亡器官捐献者(DBD)占器官捐献的大多数:目的:确定引导重症监护医师将脑死亡患者鉴定为潜在器官捐献者的因素,以及对鉴定决定有重大影响的因素是否构成实际禁忌症:我们根据 2010-2020 年西里西亚重症监护室登记处的数据和 Poltransplant 的公开信息进行了一项回顾性研究。我们比较了被确诊为符合和不符合器官捐献条件的脑死亡患者的人口统计学和临床特征:在西里西亚重症监护室登记处登记的 25465 名患者中,有 385 人(1.51%)被诊断为脑死亡,其中 61 份记录因数据不完整而被排除。剩下的一组(n = 324)中有 201 名男性和 123 名女性。其中,只有 180 名研究参与者符合捐献条件(55.5%)。6名患者有器官捐献的绝对禁忌症:结论:相对较少的脑死亡患者被重症监护医生认定为符合器官捐献条件,影响这一决定的医学因素有限。这意味着其他非医疗因素可能会影响脑死亡患者的器官获取资格。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
What do we know about eligible organ donors? Analysis of data from a local Registry.

Background: The imbalance between supply and demand for organ donations remains a hot topic for international debate. Brain-dead organ donors (DBDs) constitute the majority of organ donations in Poland.

Objectives: To identify the factors that guided intensivists in qualifying a brain-dead patient as a potential organ donor, and whether the factors that significantly influenced the decision to qualify constituted an actual contraindication.

Material and methods: We performed a retrospective study based on data from the Silesian ICU Registry from 2010-2020 and publicly available information from Poltransplant. We compared the demographic and clinical characteristics of patients diagnosed with brain death who were identified as eligible and ineligible organ donors.

Results: Out of 25,465 patients enrolled in the Silesian ICU Registry, brain death was diagnosed in 385 (1.51%) study participants, and 61 of the records were excluded due to data incompleteness. In the remaining group (n = 324), there were 201 men and 123 women. Of them, only 180 study participants were reported as eligible donors (55.5%). Six patients had absolute contraindications to organ donation.

Conclusions: A relatively small number of patients diagnosed with brain death were qualified by intensivists as eligible organ donors, with a limited number of medical factors influencing this decision. This means that other non-medical factors may affect the qualification of DBDs for organ procurement.

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来源期刊
Advances in Clinical and Experimental Medicine
Advances in Clinical and Experimental Medicine MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
3.70
自引率
4.80%
发文量
153
审稿时长
6-12 weeks
期刊介绍: Advances in Clinical and Experimental Medicine has been published by the Wroclaw Medical University since 1992. Establishing the medical journal was the idea of Prof. Bogumił Halawa, Chair of the Department of Cardiology, and was fully supported by the Rector of Wroclaw Medical University, Prof. Zbigniew Knapik. Prof. Halawa was also the first editor-in-chief, between 1992-1997. The journal, then entitled "Postępy Medycyny Klinicznej i Doświadczalnej", appeared quarterly. Prof. Leszek Paradowski was editor-in-chief from 1997-1999. In 1998 he initiated alterations in the profile and cover design of the journal which were accepted by the Editorial Board. The title was changed to Advances in Clinical and Experimental Medicine. Articles in English were welcomed. A number of outstanding representatives of medical science from Poland and abroad were invited to participate in the newly established International Editorial Staff. Prof. Antonina Harłozińska-Szmyrka was editor-in-chief in years 2000-2005, in years 2006-2007 once again prof. Leszek Paradowski and prof. Maria Podolak-Dawidziak was editor-in-chief in years 2008-2016. Since 2017 the editor-in chief is prof. Maciej Bagłaj. Since July 2005, original papers have been published only in English. Case reports are no longer accepted. The manuscripts are reviewed by two independent reviewers and a statistical reviewer, and English texts are proofread by a native speaker. The journal has been indexed in several databases: Scopus, Ulrich’sTM International Periodicals Directory, Index Copernicus and since 2007 in Thomson Reuters databases: Science Citation Index Expanded i Journal Citation Reports/Science Edition. In 2010 the journal obtained Impact Factor which is now 1.179 pts. Articles published in the journal are worth 15 points among Polish journals according to the Polish Committee for Scientific Research and 169.43 points according to the Index Copernicus. Since November 7, 2012, Advances in Clinical and Experimental Medicine has been indexed and included in National Library of Medicine’s MEDLINE database. English abstracts printed in the journal are included and searchable using PubMed http://www.ncbi.nlm.nih.gov/pubmed.
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