发现癌症非整倍体的新驱动因素

IF 72.5 1区医学 Q1 ONCOLOGY

Nature Reviews Cancer Pub Date : 2024-02-09 DOI:10.1038/s41568-024-00671-0

Juliann Shih

引用次数: 0

摘要

在这篇《贸易工具》（Tools of the Trade）中，Juliann Shih 介绍了 BISCUT 的开发情况。BISCUT 可通过询问部分体细胞拷贝数改变的长度分布来检测具有适应性优势或劣势的基因组位点，从而发现癌症非整倍体的新驱动因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Discovering new drivers of cancer aneuploidy

In this Tools of the Trade, Juliann Shih describes the development of BISCUT, which detects genomic loci that are subject to fitness advantages or disadvantages by interrogating the length distributions of partial somatic copy-number alterations to enable the discovery of new drivers of aneuploidy in cancer.

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来源期刊

Nature Reviews Cancer 医学-肿瘤学

CiteScore

111.90

自引率

0.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cancer, a part of the Nature Reviews portfolio of journals, aims to be the premier source of reviews and commentaries for the scientific communities it serves. The correct abbreviation for abstracting and indexing purposes is Nat. Rev. Cancer. The international standard serial numbers (ISSN) for Nature Reviews Cancer are 1474-175X (print) and 1474-1768 (online). Unlike other journals, Nature Reviews Cancer does not have an external editorial board. Instead, all editorial decisions are made by a team of full-time professional editors who are PhD-level scientists. The journal publishes Research Highlights, Comments, Reviews, and Perspectives relevant to cancer researchers, ensuring that the articles reach the widest possible audience due to their broad scope.