用 1440 和 1927 波长低功率二极管激光点阵治疗颈部和胸部年轻化。

IF 2.2 3区 医学 Q2 DERMATOLOGY
Lauren Hoffman MD, Eleanor Smeallie BS, Nkem Ugonabo MD, MPH, Anne Chapas MD
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引用次数: 0

摘要

目的:紫外线和红外线照射到胸部和颈部会导致光老化变化,如皱纹、皮肤粗糙和色素沉着,可以用非烧蚀分次激光治疗。低功率的 1440 和 1927 纳米分段式二极管激光器已被证明可以安全地减少面部光损伤。本研究旨在探讨低功率 1440 和 1927 纳米非烧蚀分段式二极管激光器在治疗颈部和胸部的光老化症状(如皱纹、皮肤粗糙和色素沉着)方面的安全性和有效性:在一项前瞻性、单臂、非随机研究中,24 名颈部和胸部光损伤的成年女性患者接受了四次治疗,每次治疗间隔四周。治疗包括使用波长为 1440 纳米的手机在高设置下进行四次治疗,然后使用波长为 1927 纳米的手机进行四次治疗。每次治疗都要拍照。研究人员在基线和第四次治疗后 3 个月的随访中对治疗部位的皱纹严重程度、纹理和斑驳色素进行评分。受试者还对颈部和胸部的临床改善情况以及整体外观进行评分。盲人评估员通过基线和随访照片,采用 6 级改善量表对颈部和胸部褶皱和色素沉着的改善情况进行量化:结果:在最初的一组受试者中,有 20 人完成了全部四次治疗和 3 个月的随访。颈部和胸部的褶皱平均得分提高了 0.7 ± 1.0。同时,颈部和胸部的纹理评分分别提高了 1.2 ± 0.4 和 1.4 ± 0.7,色素评分分别提高了 0.5 ± 0.6 和 0.67 ± 0.7。使用配对 t 检验对治疗前后的所有评分进行统计分析,结果显示差异显著(p 结论):使用非烧蚀低能量点阵 1440 和 1927 纳米二极管激光器进行一系列治疗,对于改善颈部和胸部的皱纹、皮肤质地和色素沉着似乎是安全有效的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neck and chest rejuvenation with fractional 1440 and 1927-nm low-powered diode laser

Objectives

Ultraviolet light and infrared radiation exposure to the chest and neck can result in photoaging changes, such as rhytids, skin roughness, and dyschromia, which can be treated with nonablative fractionated lasers. The low-powered fractionated 1440 and 1927-nm diode lasers have been shown to safely reduce facial photodamage. This study was conducted to investigate the safety and efficacy of a low-powered 1440 and 1927-nm nonablative fractionated diode laser in addressing photoaging symptoms, such as rhytids, skin roughness, and dyschromia, of the neck and chest.

Methods

In a prospective, single-arm, nonrandomized study, a cohort of 24 adult female patients with photodamage to their neck and chest received four treatments to these areas, administered at 4-week intervals. Treatments consisted of four passes on high settings with the 1440 nm handpiece followed by four passes with the 1927 nm handpiece. Photographs were taken at each study visit. Study investigators graded wrinkle severity, texture, and mottled pigmentation of the treated area at baseline and follow-up visit, 3 months after the fourth treatment. Subjects also rated clinical improvement of their neck and chest, along with overall appearance. Blinded evaluators used baseline and follow-up photographs to quantify improvements of rhytids and hyperpigmentation of the neck and chest using a 6-point improvement scale.

Results

Of the original cohort, 20 subjects completed all four treatments and 3-month follow-ups. The mean rhytid scores improved by 0.7 ± 1.0 for both neck and chest. Meanwhile, texture scores improved by 1.2 ± 0.4 for the neck and 1.4 ± 0.7 for the chest, with pigment scores improving by 0.5 ± 0.6 for the neck and 0.67 ± 0.7 for the chest. Statistical analysis using paired t-tests, performed on all pre- and posttreatment scores, revealed significant differences (p < 0.05) in wrinkle severity, skin texture, and pigmentation of the neck and chest posttreatment. The degree of improvement was consistent for both the neck and chest areas. Blinded evaluators graded clinical improvements in rhytids and pigmentation at 0.6 ± 1.0 and 0.8 ± 1.2 respectively, corresponding to mild improvement of both neck and chest.

Conclusions

A series of treatments with the nonablative low-energy fractional 1440 and 1927-nm diode laser appears to be safe and effective for improving rhytids, skin texture, and hyperpigmentation of the neck and chest.

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来源期刊
CiteScore
5.40
自引率
12.50%
发文量
119
审稿时长
1 months
期刊介绍: Lasers in Surgery and Medicine publishes the highest quality research and clinical manuscripts in areas relating to the use of lasers in medicine and biology. The journal publishes basic and clinical studies on the therapeutic and diagnostic use of lasers in all the surgical and medical specialties. Contributions regarding clinical trials, new therapeutic techniques or instrumentation, laser biophysics and bioengineering, photobiology and photochemistry, outcomes research, cost-effectiveness, and other aspects of biomedicine are welcome. Using a process of rigorous yet rapid review of submitted manuscripts, findings of high scientific and medical interest are published with a minimum delay.
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