修复兔子气管部分缺损的胸锁乳突肌瓣。

Acta cirurgica brasileira Pub Date : 2024-02-05 eCollection Date: 2024-01-01 DOI:10.1590/acb390324
Gustavo Fernandes, Ariadne Rein, Gabriel Luiz Montanhim, Marcelo Carrijo da Costa, Marcella Dall'Agnol Leite, Nicolle Pereira Soares, Paola Castro Moraes
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引用次数: 0

摘要

目的:本研究旨在评估用肌肉瓣修复气管部分缺损的效果,这是一种采用联合缝合模式的先进技术:方法:以 16 只健康雄性新西兰白兔为实验模型。方法:以 16 只健康的雄性新西兰白兔为实验模型,在第四至第八气管环的腹侧区域创建部分气管缺损。随后,用胸骨肌皮瓣进行修复。动物被分为四组,通过临床、气管镜和组织病理学分析进行术后评估。每组根据安乐死的时间分为7天组(G7)、15天组(G15)、30天组(G30)和60天组(G60):G60 组有一只动物死亡,而其他动物手术后恢复良好,呼吸模式没有发生严重变化。观察到的主要临床症状是喘鸣和咳嗽。气管镜检查发现气管腔内有分泌物、大量肉芽和狭窄。组织病理学分析显示,植入皮瓣 30 天后,皮瓣部位的纤毛呼吸道上皮增生:由于肌肉的解剖位置、充分的血管支持、结构和生理上的维护,部分修复术取得了令人满意的效果,呼吸系统没有发生严重变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Flap of the sternocephalicus muscle in the repair of a partial defect in the trachea of a rabbit (Oryctolagus cuniculus).

Purpose: The current study aimed at evaluating the repair of a partial defect of the trachea with a muscle flap, an advanced technique that employs combined suture patterns.

Methods: Sixteen healthy male New Zealand white rabbits were used as an experimental model. A partial defect in the trachea within the ventral region of the fourth to eighth tracheal ring was created. Subsequently, repair was initiated with a flap of the sternocephalicus muscle. The animals were divided into four groups for postoperative evaluation using clinical, tracheoscopic, and histopathological analyses. Each group was separated according to the time of euthanasia, programmed at interval of seven (G7), 15 (G15), 30 (G30), and 60 days (G60).

Results: One animal from the G60 group died, whereas the other animals had good surgical recovery without serious changes in the breathing pattern. The major clinical signs observed were stridor and coughing. Tracheoscopy revealed secretions in the tracheal lumen, exuberant granulation, and stenosis. Histopathological analysis showed growth of the ciliary respiratory epithelium at the flap site 30 days after implantation.

Conclusions: Partial repair showed satisfactory results owing to the anatomical location of the muscle, adequate vascular support, and structural and physiological maintenance without serious changes in the respiratory system.

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