{"title":"夏威夷原住民和太平洋岛民的合并症与认知障碍有关。","authors":"Archana J McEligot, Ka'ala Pang, Sabrina Moran-Gomez, Sinjini Mitra, Mariella Santos, Zahra Tahmasebi, Sanam Kazemi","doi":"10.1177/00914150241231186","DOIUrl":null,"url":null,"abstract":"<p><p>We examined the association between comorbid conditions and mild cognitive impairment (MCI) in Native Hawaiians and Pacific Islanders (NHPI) (<i>n</i> = 54). Cross-sectional, self-reported questionnaires were utilized to collect demographic, comorbid conditions, and MCI (via the AD8 index) data. Separate logistic regression models were conducted to investigate the relationship between comorbid conditions and MCI, adjusting for other covariates. We found significantly increased odds of MCI in those reporting high blood pressure (OR = 5.27; 95% CI: [1.36, 20.46]; <i>p</i> = 0.016), high cholesterol (OR = 7.30; 95% CI: [1.90, 28.14], <i>p </i>= 0.004), and prediabetes or borderline diabetes (OR = 4.53; 95% CI: [1.27, 16.16], <i>p </i>= 0.02) compared with those not reporting these respective conditions. These data show that hypertension, hypercholesterolemia, and prediabetes are associated with MCI in the NHPI community, suggesting that preventive strategies to reduce chronic conditions may also potentially slow cognitive decline in underrepresented/understudied NHPI.</p>","PeriodicalId":47878,"journal":{"name":"International Journal of Aging & Human Development","volume":" ","pages":"420-433"},"PeriodicalIF":1.2000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11303594/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comorbid Conditions Are Associated With Cognitive Impairment in Native Hawaiians and Pacific Islanders.\",\"authors\":\"Archana J McEligot, Ka'ala Pang, Sabrina Moran-Gomez, Sinjini Mitra, Mariella Santos, Zahra Tahmasebi, Sanam Kazemi\",\"doi\":\"10.1177/00914150241231186\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>We examined the association between comorbid conditions and mild cognitive impairment (MCI) in Native Hawaiians and Pacific Islanders (NHPI) (<i>n</i> = 54). Cross-sectional, self-reported questionnaires were utilized to collect demographic, comorbid conditions, and MCI (via the AD8 index) data. Separate logistic regression models were conducted to investigate the relationship between comorbid conditions and MCI, adjusting for other covariates. We found significantly increased odds of MCI in those reporting high blood pressure (OR = 5.27; 95% CI: [1.36, 20.46]; <i>p</i> = 0.016), high cholesterol (OR = 7.30; 95% CI: [1.90, 28.14], <i>p </i>= 0.004), and prediabetes or borderline diabetes (OR = 4.53; 95% CI: [1.27, 16.16], <i>p </i>= 0.02) compared with those not reporting these respective conditions. These data show that hypertension, hypercholesterolemia, and prediabetes are associated with MCI in the NHPI community, suggesting that preventive strategies to reduce chronic conditions may also potentially slow cognitive decline in underrepresented/understudied NHPI.</p>\",\"PeriodicalId\":47878,\"journal\":{\"name\":\"International Journal of Aging & Human Development\",\"volume\":\" \",\"pages\":\"420-433\"},\"PeriodicalIF\":1.2000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11303594/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Aging & Human Development\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/00914150241231186\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/2/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"GERONTOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Aging & Human Development","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/00914150241231186","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/7 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"GERONTOLOGY","Score":null,"Total":0}
Comorbid Conditions Are Associated With Cognitive Impairment in Native Hawaiians and Pacific Islanders.
We examined the association between comorbid conditions and mild cognitive impairment (MCI) in Native Hawaiians and Pacific Islanders (NHPI) (n = 54). Cross-sectional, self-reported questionnaires were utilized to collect demographic, comorbid conditions, and MCI (via the AD8 index) data. Separate logistic regression models were conducted to investigate the relationship between comorbid conditions and MCI, adjusting for other covariates. We found significantly increased odds of MCI in those reporting high blood pressure (OR = 5.27; 95% CI: [1.36, 20.46]; p = 0.016), high cholesterol (OR = 7.30; 95% CI: [1.90, 28.14], p = 0.004), and prediabetes or borderline diabetes (OR = 4.53; 95% CI: [1.27, 16.16], p = 0.02) compared with those not reporting these respective conditions. These data show that hypertension, hypercholesterolemia, and prediabetes are associated with MCI in the NHPI community, suggesting that preventive strategies to reduce chronic conditions may also potentially slow cognitive decline in underrepresented/understudied NHPI.
期刊介绍：
These are some of the broad questions with which the International Journal of Aging and Human Development is concerned. Emphasis is upon psychological and social studies of aging and the aged. However, the Journal also publishes research that introduces observations from other fields that illuminate the "human" side of gerontology, or utilizes gerontological observations to illuminate in other fields.
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