肌腱/韧带-骨界面的结构、生物学和机械功能。

IF 5.1 2区医学 Q2 CELL & TISSUE ENGINEERING

Tissue Engineering. Part B, Reviews Pub Date : 2024-10-01 Epub Date: 2024-03-05 DOI:10.1089/ten.TEB.2023.0295

Huizhi Wang, Kaixin He, Cheng-Kung Cheng

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引用次数: 0

摘要

肌腱或韧带重建后，硬骨和软结缔组织之间的界面会大大减弱，很难通过愈合恢复。肌腱/韧带-骨界面在拉伸载荷作用下是力学上最薄弱的部位，通常是各种术后并发症（如骨吸收和移植物松弛）的根源。全面了解原生肌腱/韧带-骨界面的宏观和微观特征有利于制定组织再生策略。本文讨论了肌腱/韧带-骨界面的结构、生物和机械特征，以及这些特征如何受到老化和负载条件的影响。影响声明本综述对肌腱/韧带-骨界面的结构、生物和机械特征以及这些特征如何受到老化和负载条件的影响进行了最新总结。对这些特征的透彻了解为开发韧带/肌腱重建和软硬组织界面工程的先进技术奠定了重要基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Structure, Biology, and Mechanical Function of Tendon/Ligament-Bone Interfaces.

After tendon or ligament reconstruction, the interface between the hard bone and soft connective tissue is considerably weakened and is difficult to restore through healing. The tendon/ligament-bone interface is mechanically the weakest point under tensile loading and is often the source of various postoperative complications, such as bone resorption and graft laxity. A comprehensive understanding of the macro- and microfeatures of the native tendon/ligament-bone interface would be beneficial for developing strategies for regenerating the tissue. This article discusses the structural, biological, and mechanical features of the tendon/ligament-bone interfaces and how these can be affected by aging and loading conditions.

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来源期刊

Tissue Engineering. Part B, Reviews Biochemistry, Genetics and Molecular Biology-Biochemistry

CiteScore

12.80

自引率

1.60%

发文量

150

期刊介绍： Tissue Engineering Reviews (Part B) meets the urgent need for high-quality review articles by presenting critical literature overviews and systematic summaries of research within the field to assess the current standing and future directions within relevant areas and technologies. Part B publishes bi-monthly.