对患有原发性闭角型青光眼的柴犬进行单纯药物治疗与艾哈迈德青光眼瓣膜植入术的视觉效果比较。

IF 1.7 4区 农林科学 Q2 VETERINARY SCIENCES
Veterinary ophthalmology Pub Date : 2024-09-01 Epub Date: 2024-02-06 DOI:10.1111/vop.13189
Akira Kubo, Yosuke Ito
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引用次数: 0

摘要

研究目的该研究旨在评估单纯药物治疗(MED)和艾哈迈德青光眼瓣膜植入术(AGVI)对患有原发性闭角型青光眼(PACG)的柴犬的视觉效果:对 65 只患有 PACG 的柴犬(104 只眼)的记录进行了回顾性审查。使用威胁反应和迷宫测试对视力进行定性评估。评估首次出现(V1)时的年龄、性别、眼压(IOP)和临床症状持续时间(≤72 小时或>72 小时)的重要性。根据后续治疗方法(MED 或 AGVI)将 V1 时有视力的眼睛分为几组,并用 Kaplan-Meier 法比较各组间视力的存活率:54只狗中有65只(62.5%)在V1时有视力。在 V1 期视力方面,年龄和性别差异无统计学意义。与视力正常的眼睛(28 mmHg)相比,失明眼睛的中位眼压更高(52 mmHg)(p 结论:AGVI 的视觉疗效优于 AGVI:与 MED 相比,AGVI 的视觉效果更好,对于患有 PACG 且发病时视力正常并适合手术的柴犬,应考虑采用 AGVI。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of visual outcomes between medical treatment alone and Ahmed glaucoma valve implantation in Shiba dogs with primary angle closure glaucoma.

Objective: The objective of the study was to evaluate visual outcomes between medical treatment alone (MED) and Ahmed glaucoma valve implantation (AGVI) in Shiba dogs with primary angle closure glaucoma (PACG).

Procedures: Records of 65 Shiba dogs (104 eyes) with PACG were retrospectively reviewed. Vision was assessed qualitatively using both the menace response and maze testing. The significance of age, sex, intraocular pressure (IOP), and duration of clinical signs (≤72 h or >72 h) at first presentation (V1) was assessed. Eyes with vision at V1 were divided into groups according to subsequent treatment method (MED versus AGVI), and vision as a survival outcome was compared between group by the Kaplan-Meier method.

Results: At V1, 65 eyes (62.5%) of 54 dogs had vision. There was no statistically significant difference in age or sex on the presence of vision at V1. Median IOP was higher in blind (52 mmHg) compared to sighted eyes (28 mmHg) (p < .001). Eyes presenting in ≤72 h of the onset of clinical signs were more likely to have vision (86.7%) compared to those presenting after 72 h (44.1%) (p < .001). By the Kaplan-Meier analysis, the cumulative visual retention rate was significantly higher with AGVI than with MED (69.2% vs. 7.7%; p < .01) at 12 months. The median time to visual loss was 39.9 months with AGVI vs. 1.7 months with MED.

Conclusions: AGVI resulted in better visual outcomes than MED and should be considered in Shiba dogs with PACG that are visual at the time of presentation and suitable for surgery.

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来源期刊
Veterinary ophthalmology
Veterinary ophthalmology 农林科学-兽医学
CiteScore
2.70
自引率
37.50%
发文量
82
审稿时长
12-24 weeks
期刊介绍: Veterinary Ophthalmology is a peer-reviewed, international journal that welcomes submission of manuscripts directed towards academic researchers of veterinary ophthalmology, specialists and general practitioners with a strong ophthalmology interest. Articles include those relating to all aspects of: Clinical and investigational veterinary and comparative ophthalmology; Prospective and retrospective studies or reviews of naturally occurring ocular disease in veterinary species; Experimental models of both animal and human ocular disease in veterinary species; Anatomic studies of the animal eye; Physiological studies of the animal eye; Pharmacological studies of the animal eye.
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