孢子发芽两个离子通道胜过一个

IF 7.5 1区生物学 Q1 CELL BIOLOGY

Genes & development Pub Date : 2024-02-13 DOI:10.1101/gad.351554.124

Patrick Eichenberger

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引用次数: 0

摘要

萌发是孢子从休眠中萌发的过程。虽然孢子可以休眠几十年，但萌发研究却是一个活跃的研究领域。在本期《基因与发育》（Genes & Development）杂志上，Gao 及其同事（第 XXX-XXX 页）探讨了一个令人困惑的问题：休眠孢子如何根据环境线索启动萌发？其中涉及三个不同的复合体：GerA 是萌发门控离子通道；5AF/FigP 是放大所需的第二个离子通道；SpoVA 是二羧酸（DPA）通道。DPA 释放后，孢子核会重新水化，从而恢复新陈代谢活动。

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Spore germination: Two ion channels are better than one.

Germination is the process by which spores emerge from dormancy. Although spores can remain dormant for decades, the study of germination is an active field of research. In this issue of Genes & Development, Gao and colleagues (pp. 31-45) address a perplexing question: How can a dormant spore initiate germination in response to environmental cues? Three distinct complexes are involved: GerA, a germinant-gated ion channel; 5AF/FigP, a second ion channel required for amplification; and SpoVA, a channel for dipicolinic acid (DPA). DPA release is followed by rehydration of the spore core, thus allowing the resumption of metabolic activity.

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来源期刊

Genes & development 生物-发育生物学

CiteScore

17.50

自引率

1.90%

发文量

审稿时长

3-6 weeks

期刊介绍： Genes & Development is a research journal published in association with The Genetics Society. It publishes high-quality research papers in the areas of molecular biology, molecular genetics, and related fields. The journal features various research formats including Research papers, short Research Communications, and Resource/Methodology papers. Genes & Development has gained recognition and is considered as one of the Top Five Research Journals in the field of Molecular Biology and Genetics. It has an impressive Impact Factor of 12.89. The journal is ranked #2 among Developmental Biology research journals, #5 in Genetics and Heredity, and is among the Top 20 in Cell Biology (according to ISI Journal Citation Reports®, 2021).