社会脆弱性、虚弱和自我感觉健康：爱尔兰老龄化纵向研究（TILDA）的发现。

IF 3.3 Q2 GERIATRICS & GERONTOLOGY

Journal of Frailty & Aging Pub Date : 2024-01-01 DOI:10.14283/jfa.2024.1

L Orlandini, E Patrizio, A M O'Halloran, C A McGarrigle, R Romero-Ortuno, R A Kenny, M Proietti, M Cesari

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引用次数: 0

摘要

背景社会脆弱性与虚弱相互影响，并影响个人的健康状况。虽然虚弱和社会脆弱性对不良后果有很高的预测性，但它们与自我感觉健康（SPH）的关系却鲜有研究：数据来自爱尔兰老龄化纵向研究（TILDA），这是一项基于人口的老龄化纵向研究。我们纳入了4222名年龄≥50岁的参与者（年龄为61.4±8.5岁；女性占56%），这些参与者来自第一波研究（2009-2011年），随后进行了三次纵向研究（2012年、2014-2015年、2016年）。受试者回答了单项问题，其中有五个回答选项，分别是：1)身体健康；2)心理健康；3)与同龄人相比的健康状况。采用标准化方法计算了 30 项虚弱（FI）和社会脆弱性（SVI）指数。进行了多变量回归分析，以确定 FI 和 SVI 在横向和纵向 6 年间的关联：横断面上，SVI（平均值：0.40±0.08；范围：0.14-0.81）和 FI（平均值：0.13±0.08；范围：0.10-0.58）呈适度相关（r=0.256），并与身体健康状况差独立相关（SVI：OR 1.43，95%CI 1.15-1.78；FI：OR 3.16，95%CI 2.54-3.93）、心理健康状况差（SVI：OR 1.65，95%CI 1.17-2.35；FI：OR 3.64，95%CI 2.53-5.24）以及与同龄人相比健康状况差（SVI：OR 1.41，95%CI 1.06-1.89；FI：OR 3.86，95%CI 2.9-5.14）。纵向来看，FI 和 SVI 与身体健康状况差（SVI：β 1.08，95%CI 0.76-1.39；FI：β 1.97，95%CI 1.58-2.36）、心理健康状况差（SVI：β 1.18，95%CI 0.86-1.5；FI：β 1.58，95%CI 1.2-1.97），与同龄人相比总体健康状况较差（SVI：β 0.78，95%CI 0.89-1.33；FI：β 1.74，95%CI 0.47-1.1）：在一个庞大的社区老年人队列中，虚弱和社会脆弱性与不良的SPH和六年内SPH下降的风险有关。

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Social Vulnerability, Frailty and Self-Perceived Health: Findings from The Irish Longitudinal Study on Ageing (TILDA).

Background: Social vulnerability interacts with frailty and influences individuals' health status. Although frailty and social vulnerability are highly predictive of adverse outcomes, their relationship with self-perceived health(SPH) has been less investigated.

Methods: Data are from the Irish Longitudinal Study on Ageing(TILDA), a population-based longitudinal study of ageing. We included 4,222 participants aged ≥50 years (age 61.4±8.5 years;women 56%) from Wave 1 (2009-2011) followed over three longitudinal waves (2012,2014-2015,2016). Participants responded to single questions with five response options to rate their 1)physical health, 2)mental health, and 3)health compared to peers. 30-item Frailty (FI) and Social Vulnerability (SVI) indices were calculated using standardised methods. Multivariable regression analyses were performed to establish the association between FI and SVI cross-sectionally and longitudinally over 6 years.

Results: Cross-sectionally, SVI (mean:0.40±0.08; range:0.14-0.81) and FI (mean: 0.13±0.08; range:0.10-0.58) were modestly correlated (r=0.256), and independently associated with poor physical health (SVI: OR 1.43, 95%CI 1.15-1.78; FI: OR 3.16, 95%CI 2.54-3.93), poor mental health (SVI: OR 1.65, 95%CI 1.17-2.35; FI: OR 3.64, 95%CI 2.53-5.24), and poor health compared to peers (SVI: OR 1.41,95%CI 1.06-1.89; FI: OR 3.86, 95%CI 2.9-5.14). Longitudinally, FI and SVI were independently and positively associated with poor physical health (SVI: β 1.08, 95%CI 0.76-1.39; FI: β 1.97, 95%CI 1.58-2.36), poor mental health (SVI: β 1.18, 95%CI 0.86-1.5; FI: β 1.58, 95%CI 1.2-1.97), and poor overall health compared to peers (SVI: β 0.78, 95%CI 0.89-1.33; FI: β 1.74, 95%CI 0.47-1.1).

Conclusions: In a large cohort of community-dwelling older adults, frailty and social vulnerability were associated with poor SPH and with risk of SPH decline over six years.

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来源期刊

Journal of Frailty & Aging GERIATRICS & GERONTOLOGY-

CiteScore

5.90

自引率

7.70%

发文量

期刊介绍： The Journal of Frailty & Aging is a peer-reviewed international journal aimed at presenting articles that are related to research in the area of aging and age-related (sub)clinical conditions. In particular, the journal publishes high-quality papers describing and discussing social, biological, and clinical features underlying the onset and development of frailty in older persons. The Journal of Frailty & Aging is composed by five different sections: - Biology of frailty and aging In this section, the journal presents reports from preclinical studies and experiences focused at identifying, describing, and understanding the subclinical pathophysiological mechanisms at the basis of frailty and aging. - Physical frailty and age-related body composition modifications Studies exploring the physical and functional components of frailty are contained in this section. Moreover, since body composition plays a major role in determining physical frailty and, at the same time, represents the most evident feature of the aging process, special attention is given to studies focused on sarcopenia and obesity at older age. - Neurosciences of frailty and aging The section presents results from studies exploring the cognitive and neurological aspects of frailty and age-related conditions. In particular, papers on neurodegenerative conditions of advanced age are welcomed. - Frailty and aging in clinical practice and public health This journal’s section is devoted at presenting studies on clinical issues of frailty and age-related conditions. This multidisciplinary section particularly welcomes reports from clinicians coming from different backgrounds and specialties dealing with the heterogeneous clinical manifestations of advanced age. Moreover, this part of the journal also contains reports on frailty- and age-related social and public health issues. - Clinical trials and therapeutics This final section contains all the manuscripts presenting data on (pharmacological and non-pharmacological) interventions aimed at preventing, delaying, or treating frailty and age-related conditions.The Journal of Frailty & Aging is a quarterly publication of original papers, review articles, case reports, controversies, letters to the Editor, and book reviews. Manuscripts will be evaluated by the editorial staff and, if suitable, by expert reviewers assigned by the editors. The journal particularly welcomes papers by researchers from different backgrounds and specialities who may want to share their views and experiences on the common themes of frailty and aging.The abstracting and indexing of the Journal of Frailty & Aging is covered by MEDLINE (approval by the National Library of Medicine in February 2016).