与髋臼发育不良有关的新型膝关节炎亚型:一个病例系列。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Patricio Iii Dumlao, Kiminori Yukata, Yutaka Suetomi, Atsunori Tokushige, Takashi Sakai, Hiroshi Fujii
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引用次数: 0

摘要

背景:多关节炎模式需要全面了解,以优化患者管理。本研究旨在介绍一组偏离已知膝关节炎(CK)定义的患者,识别并描述这一非典型群体:对2008年1月至2018年12月期间接受全髋关节置换术和全膝关节置换术的患者进行回顾性研究。患者被分为典型髋关节炎膝关节组(典型、长腿关节病和风湿畸形)和非典型髋关节炎膝关节组。对两组患者的腿长差异、体重指数(BMI)和影像学参数进行了比较和分析:共有 31 名患者被分配到典型髋关节炎膝关节组(10 人)和非典型髋关节炎膝关节组(21 人)。在非典型组中,有27个髋关节受累,其中21个有髋臼发育不良,5个表现为软骨下发育不全骨折样改变,只有1个有典型的骨关节炎。在接受全膝关节置换术的 27 个膝关节中,26 个膝关节呈屈曲排列,1 个在正常范围内,没有膝关节外翻。髋臼发育不良涉及同侧(1 例)、对侧(14 例)和双侧(6 例)髋关节,表现为非典型膝髋关节炎。髋臼发育不良的患者更有可能表现出不典型的CK:结论:队列中的大多数患者表现为髋臼发育不良和对侧膝关节外翻,构成了一种称为 "髋臼发育不良相关性膝关节炎 "的模式。对于髋臼发育不良和膝外翻高发的高危地区来说,识别这种新型亚型可能具有重要的临床意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Novel subtype of coxitis knee associated with acetabular dysplasia of the hip: a case series.

Background: Multiple joint arthritis patterns require a comprehensive understanding to optimize patient management. This study aimed to present a patient cohort that deviated from known definitions of coxitis knee (CK), identifying and characterizing this atypical group.

Methods: Patients undergoing both total hip arthroplasty and total knee arthroplasty between January 2008 and December 2018 were retrospectively reviewed. The patients were classified into a typical coxitis knee group (classic, long leg arthropathy, and windswept deformity) and an atypical coxitis knee group. Leg-length discrepancy, body mass index (BMI), and radiographic parameters of the groups were compared and analyzed.

Results: A total of 31 patients were allocated to the typical coxitis knee group (n = 10), and atypical coxitis knee group (n = 21). In the atypical group, 27 hips were involved, of which 21 had acetabular dysplasia, 5 exhibited subchondral insufficiency fracture-like changes, and only 1 had classic osteoarthritis. Among the 27 knees undergoing total knee arthroplasty, 26 showed varus alignment, 1 was within the normal range, and none was valgus. Acetabular dysplasia involved ipsilateral (n = 1), contralateral (n = 14), and bilateral (n = 6) hips, showing atypical coxitis knee. Patients with acetabular dysplasia were more likely to exhibit atypical CK.

Conclusion: Most patients in the cohort displayed acetabular dysplasia and contralateral varus knees, constituting a pattern referred to as acetabular dysplasia-associated gonarthritis. Identifying this novel subtype may have important clinical implications for regions with high risk factors, where acetabular dysplasia and constitutional genu varum are prevalent.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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