{"title":"整形显微外科医生在肝脏移植中的作用--综述。","authors":"Min Kai Chang, Andre Eu Jin Cheah","doi":"10.21037/atm-23-519","DOIUrl":null,"url":null,"abstract":"<p><strong>Background and objective: </strong>Liver transplantation is a life-saving procedure, but also associated with complications. Hepatic artery thrombosis is one of the most devastating complications, especially for living donor liver transplantation. The application of microsurgical techniques for hepatic artery reconstruction has greatly reduced the risk of hepatic artery thrombosis. In this narrative review, we discuss the technical considerations and challenges faced in microsurgical reconstruction of hepatic artery in liver transplantation.</p><p><strong>Methods: </strong>PubMed, Web of Science, and Google Scholar were searched for keywords relating to \"liver transplantation\", \"microsurgery\", \"living donor liver transplantation\", \"deceased donor liver transplantation\", \"hepatic artery\", \"hepatic artery thrombosis\", \"hepatic artery reconstruction\" and \"microsurgical anastomosis\". Relevant articles pertaining to the technical considerations and challenges of microsurgery in liver transplantation were included.</p><p><strong>Key content and findings: </strong>The conditions of liver transplantation pose unique challenges to the microsurgeon. Nonetheless, there are described strategies that can overcome these conditions, as well as technical details that may improve the outcomes of hepatic artery reconstruction. These strategies start from proper positioning of the patient, conscientious selection of donor and recipient hepatic vessels, and minimizing movements during critical microsurgical anastomosis. Technical details include techniques to overcome vessel delamination, size mismatch, poor quality vessels, and short vessel stump. This review also explores the outcomes of microsurgical hepatic arterial reconstruction.</p><p><strong>Conclusions: </strong>There are various strategies to mitigate the challenges of microsurgery in liver transplant. Microsurgery improves the outcome of liver transplantation. Microsurgeons will continue to be a priceless resource that all liver transplant teams should have.</p>","PeriodicalId":8216,"journal":{"name":"Annals of translational medicine","volume":"12 1","pages":"10"},"PeriodicalIF":0.0000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10777240/pdf/","citationCount":"0","resultStr":"{\"title\":\"The role of reconstructive microsurgeons in liver transplantation-a narrative review.\",\"authors\":\"Min Kai Chang, Andre Eu Jin Cheah\",\"doi\":\"10.21037/atm-23-519\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background and objective: </strong>Liver transplantation is a life-saving procedure, but also associated with complications. Hepatic artery thrombosis is one of the most devastating complications, especially for living donor liver transplantation. The application of microsurgical techniques for hepatic artery reconstruction has greatly reduced the risk of hepatic artery thrombosis. In this narrative review, we discuss the technical considerations and challenges faced in microsurgical reconstruction of hepatic artery in liver transplantation.</p><p><strong>Methods: </strong>PubMed, Web of Science, and Google Scholar were searched for keywords relating to \\\"liver transplantation\\\", \\\"microsurgery\\\", \\\"living donor liver transplantation\\\", \\\"deceased donor liver transplantation\\\", \\\"hepatic artery\\\", \\\"hepatic artery thrombosis\\\", \\\"hepatic artery reconstruction\\\" and \\\"microsurgical anastomosis\\\". Relevant articles pertaining to the technical considerations and challenges of microsurgery in liver transplantation were included.</p><p><strong>Key content and findings: </strong>The conditions of liver transplantation pose unique challenges to the microsurgeon. Nonetheless, there are described strategies that can overcome these conditions, as well as technical details that may improve the outcomes of hepatic artery reconstruction. These strategies start from proper positioning of the patient, conscientious selection of donor and recipient hepatic vessels, and minimizing movements during critical microsurgical anastomosis. Technical details include techniques to overcome vessel delamination, size mismatch, poor quality vessels, and short vessel stump. This review also explores the outcomes of microsurgical hepatic arterial reconstruction.</p><p><strong>Conclusions: </strong>There are various strategies to mitigate the challenges of microsurgery in liver transplant. Microsurgery improves the outcome of liver transplantation. Microsurgeons will continue to be a priceless resource that all liver transplant teams should have.</p>\",\"PeriodicalId\":8216,\"journal\":{\"name\":\"Annals of translational medicine\",\"volume\":\"12 1\",\"pages\":\"10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10777240/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of translational medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21037/atm-23-519\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/12/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of translational medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21037/atm-23-519","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/12/7 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
背景和目的:肝脏移植是一项挽救生命的手术,但也存在并发症。肝动脉血栓是最具破坏性的并发症之一,尤其是对活体肝移植而言。肝动脉重建显微外科技术的应用大大降低了肝动脉血栓形成的风险。在这篇叙述性综述中,我们讨论了肝移植肝动脉显微外科重建的技术注意事项和面临的挑战:方法:在 PubMed、Web of Science 和 Google Scholar 上搜索与 "肝移植"、"显微外科"、"活体肝移植"、"死体肝移植"、"肝动脉"、"肝动脉血栓"、"肝动脉重建 "和 "显微外科吻合术 "相关的关键词。主要内容和研究结果:肝移植的条件给显微外科医生带来了独特的挑战。然而,有一些描述的策略可以克服这些条件,还有一些技术细节可以改善肝动脉重建的结果。这些策略从病人的正确定位、供体和受体肝血管的认真选择以及在关键的显微外科吻合过程中尽量减少移动等方面入手。技术细节包括克服血管分层、大小不匹配、血管质量差和血管残端短等问题的技术。本综述还探讨了显微外科肝动脉重建的结果:结论:有多种策略可以减轻肝移植显微手术的挑战。显微手术可改善肝移植的疗效。显微外科医生将继续成为所有肝移植团队都应拥有的无价资源。
The role of reconstructive microsurgeons in liver transplantation-a narrative review.
Background and objective: Liver transplantation is a life-saving procedure, but also associated with complications. Hepatic artery thrombosis is one of the most devastating complications, especially for living donor liver transplantation. The application of microsurgical techniques for hepatic artery reconstruction has greatly reduced the risk of hepatic artery thrombosis. In this narrative review, we discuss the technical considerations and challenges faced in microsurgical reconstruction of hepatic artery in liver transplantation.
Methods: PubMed, Web of Science, and Google Scholar were searched for keywords relating to "liver transplantation", "microsurgery", "living donor liver transplantation", "deceased donor liver transplantation", "hepatic artery", "hepatic artery thrombosis", "hepatic artery reconstruction" and "microsurgical anastomosis". Relevant articles pertaining to the technical considerations and challenges of microsurgery in liver transplantation were included.
Key content and findings: The conditions of liver transplantation pose unique challenges to the microsurgeon. Nonetheless, there are described strategies that can overcome these conditions, as well as technical details that may improve the outcomes of hepatic artery reconstruction. These strategies start from proper positioning of the patient, conscientious selection of donor and recipient hepatic vessels, and minimizing movements during critical microsurgical anastomosis. Technical details include techniques to overcome vessel delamination, size mismatch, poor quality vessels, and short vessel stump. This review also explores the outcomes of microsurgical hepatic arterial reconstruction.
Conclusions: There are various strategies to mitigate the challenges of microsurgery in liver transplant. Microsurgery improves the outcome of liver transplantation. Microsurgeons will continue to be a priceless resource that all liver transplant teams should have.
期刊介绍:
The Annals of Translational Medicine (Ann Transl Med; ATM; Print ISSN 2305-5839; Online ISSN 2305-5847) is an international, peer-reviewed Open Access journal featuring original and observational investigations in the broad fields of laboratory, clinical, and public health research, aiming to provide practical up-to-date information in significant research from all subspecialties of medicine and to broaden the readers’ vision and horizon from bench to bed and bed to bench. It is published quarterly (April 2013- Dec. 2013), monthly (Jan. 2014 - Feb. 2015), biweekly (March 2015-) and openly distributed worldwide. Annals of Translational Medicine is indexed in PubMed in Sept 2014 and in SCIE in 2018. Specific areas of interest include, but not limited to, multimodality therapy, epidemiology, biomarkers, imaging, biology, pathology, and technical advances related to medicine. Submissions describing preclinical research with potential for application to human disease, and studies describing research obtained from preliminary human experimentation with potential to further the understanding of biological mechanism underlying disease are encouraged. Also warmly welcome are studies describing public health research pertinent to clinic, disease diagnosis and prevention, or healthcare policy. With a focus on interdisciplinary academic cooperation, ATM aims to expedite the translation of scientific discovery into new or improved standards of management and health outcomes practice.