烟草和医用大麻卷烟在微粒物质方面的比较。

IF 3.1 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Cannabis and Cannabinoid Research Pub Date : 2024-12-01 Epub Date: 2024-01-31 DOI:10.1089/can.2023.0201
Fenna Janssen, Markus Braun, Janis Dröge, Dörthe Brüggmann, David A Groneberg
{"title":"烟草和医用大麻卷烟在微粒物质方面的比较。","authors":"Fenna Janssen, Markus Braun, Janis Dröge, Dörthe Brüggmann, David A Groneberg","doi":"10.1089/can.2023.0201","DOIUrl":null,"url":null,"abstract":"<p><p><b>Introduction:</b> Cannabis is a widely used drug like tobacco and alcohol. In the meantime, it is also prescribed for medical treatment in some countries. Tobacco smoke contains chemical carcinogens and particulate matter (PM) that are both harmful to health. <b>Method:</b> In this study, we investigated PM levels in second-hand smoke (SHS) of hand-tamped cannabis cigarettes compared to cigarettes with tubing tobacco and the 3R4F reference cigarette. <b>Results:</b> It could be demonstrated that the largest proportion of the particle mass is attributable to particles with a diameter of less than 1μm and that every tested cigarette emitted more PM than the 3R4F reference cigarette. In addition, our data clearly revealed that cannabis smoke contains higher PM levels in SHS than tobacco cigarettes. Compared to the reference cigarette, the PM<sub>1</sub> emissions of cannabis were 105% higher. Also, the cannabis mixed cigarettes had higher PM levels than the 3R4F cigarettes. For instance, the PM<sub>10</sub> emissions were 93% higher. Also, the Gauloises Mélange tubing tobacco also reached higher PM concentrations than the 3R4F cigarette. <b>Discussion:</b> Regardless of negative health effects, cannabis is seen as a harmless drug in the public eye. We found strong indications for potential health risks by PM from cannabis products and, therefore, the public should be educated about a potential harm.</p>","PeriodicalId":9386,"journal":{"name":"Cannabis and Cannabinoid Research","volume":" ","pages":"1492-1499"},"PeriodicalIF":3.1000,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison Between Smoked Tobacco and Medical Cannabis Cigarettes Concerning Particulate Matter.\",\"authors\":\"Fenna Janssen, Markus Braun, Janis Dröge, Dörthe Brüggmann, David A Groneberg\",\"doi\":\"10.1089/can.2023.0201\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Introduction:</b> Cannabis is a widely used drug like tobacco and alcohol. In the meantime, it is also prescribed for medical treatment in some countries. Tobacco smoke contains chemical carcinogens and particulate matter (PM) that are both harmful to health. <b>Method:</b> In this study, we investigated PM levels in second-hand smoke (SHS) of hand-tamped cannabis cigarettes compared to cigarettes with tubing tobacco and the 3R4F reference cigarette. <b>Results:</b> It could be demonstrated that the largest proportion of the particle mass is attributable to particles with a diameter of less than 1μm and that every tested cigarette emitted more PM than the 3R4F reference cigarette. In addition, our data clearly revealed that cannabis smoke contains higher PM levels in SHS than tobacco cigarettes. Compared to the reference cigarette, the PM<sub>1</sub> emissions of cannabis were 105% higher. Also, the cannabis mixed cigarettes had higher PM levels than the 3R4F cigarettes. For instance, the PM<sub>10</sub> emissions were 93% higher. Also, the Gauloises Mélange tubing tobacco also reached higher PM concentrations than the 3R4F cigarette. <b>Discussion:</b> Regardless of negative health effects, cannabis is seen as a harmless drug in the public eye. We found strong indications for potential health risks by PM from cannabis products and, therefore, the public should be educated about a potential harm.</p>\",\"PeriodicalId\":9386,\"journal\":{\"name\":\"Cannabis and Cannabinoid Research\",\"volume\":\" \",\"pages\":\"1492-1499\"},\"PeriodicalIF\":3.1000,\"publicationDate\":\"2024-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cannabis and Cannabinoid Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1089/can.2023.0201\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/31 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"PHARMACOLOGY & PHARMACY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cannabis and Cannabinoid Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1089/can.2023.0201","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/31 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

摘要

简介大麻与烟草和酒精一样,是一种被广泛使用的毒品。与此同时,在一些国家,大麻也被用于医疗。烟草烟雾中含有化学致癌物质和微粒物质(PM),这两种物质都对健康有害。研究方法在这项研究中,我们调查了手压大麻卷烟与管装烟草卷烟和 3R4F 参考卷烟相比,其二手烟(SHS)中的可吸入颗粒物水平。结果显示结果表明,直径小于 1 微米的颗粒占颗粒质量的最大比例,而且每种测试香烟排放的可吸入颗粒物都多于 3R4F 参考香烟。此外,我们的数据清楚地表明,大麻烟雾中的可吸入颗粒物含量高于烟草香烟。与参考香烟相比,大麻的 PM1 排放量高出 105%。此外,大麻混合香烟的可吸入颗粒物含量也高于 3R4F 香烟。例如,PM10 的排放量高出 93%。此外,Gauloises Mélange 管装烟草的 PM 浓度也高于 3R4F 卷烟。讨论:尽管大麻对健康有负面影响,但在公众眼中它是一种无害的药物。我们发现有强烈迹象表明,大麻产品中的可吸入颗粒物可能会对健康造成危害,因此,应该对公众进行有关潜在危害的教育。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison Between Smoked Tobacco and Medical Cannabis Cigarettes Concerning Particulate Matter.

Introduction: Cannabis is a widely used drug like tobacco and alcohol. In the meantime, it is also prescribed for medical treatment in some countries. Tobacco smoke contains chemical carcinogens and particulate matter (PM) that are both harmful to health. Method: In this study, we investigated PM levels in second-hand smoke (SHS) of hand-tamped cannabis cigarettes compared to cigarettes with tubing tobacco and the 3R4F reference cigarette. Results: It could be demonstrated that the largest proportion of the particle mass is attributable to particles with a diameter of less than 1μm and that every tested cigarette emitted more PM than the 3R4F reference cigarette. In addition, our data clearly revealed that cannabis smoke contains higher PM levels in SHS than tobacco cigarettes. Compared to the reference cigarette, the PM1 emissions of cannabis were 105% higher. Also, the cannabis mixed cigarettes had higher PM levels than the 3R4F cigarettes. For instance, the PM10 emissions were 93% higher. Also, the Gauloises Mélange tubing tobacco also reached higher PM concentrations than the 3R4F cigarette. Discussion: Regardless of negative health effects, cannabis is seen as a harmless drug in the public eye. We found strong indications for potential health risks by PM from cannabis products and, therefore, the public should be educated about a potential harm.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Cannabis and Cannabinoid Research
Cannabis and Cannabinoid Research PHARMACOLOGY & PHARMACY-
CiteScore
6.80
自引率
7.90%
发文量
164
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信