Adrian Rojas Murguia, Fernando Segovia, Fatih Ayvali, Michael Brockman, Swathi Prakash, Vishwajeet Singh, Alok Kumar Dwivedi, Manu Rajachandran, Debabrata Mukherjee, Nils P Nickel
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引用次数: 0
摘要
风险分层在急性肺栓塞(PE)的管理中起着至关重要的作用。目前已研究出几种风险评分方法来支持风险分层和管理。虽然急性 PE 风险因素存在种族差异,但目前的风险评分缺乏对西班牙裔患者的验证。因此,本研究回顾性调查了肺栓塞严重程度指数(PESI)、简化肺栓塞严重程度指数(sPESI)、欧洲心脏病学会风险评估(ESC)和博瓦评分在预测西班牙裔急性 PE 患者 30 天死亡率方面的表现。在入院的 437 名急性 PE 患者中,30 天死亡率为 10.8%;低风险组的 30 天死亡率从 0% (sPESI、ESC)到 0.2%(PESI、Bova)不等,高风险组的 30 天死亡率从 3.0%(Bova)到 5.7%(PESI)不等。所有四种评分在统计学上都能显著区分不同的风险分层。但是,没有一种评分系统能够识别所有 30 天死亡的患者。本研究的结果表明,PESI、sPESI、ESC 和 Bova 评分为西班牙裔急性 PE 住院患者的 30 天死亡率提供了重要信息。然而,额外的临床信息可进一步提高预测能力,而这是单一评分系统无法提供的。
Evaluation of Four Validated Risk Scores to Predict Outcomes in Hispanic Patients With Acute Pulmonary Embolism.
Risk stratification plays an essential role in the management of acute pulmonary embolism (PE). Several risk scores have been studied to support risk stratification and management. While ethnic differences in acute PE risk factors exist, current risk scores lack validation for Hispanic patients. Therefore, the present study retrospectively investigated the performance of the pulmonary embolism severity index (PESI), simplified PESI (sPESI), the European Society of Cardiology risk assessment (ESC), and the Bova score, to predict 30-day mortality in Hispanic patients presenting with an acute PE. Among 437 patients admitted with acute PE, 30-day mortality was 10.8%; 30-day mortality in low-risk groups ranged from 0% (sPESI, ESC) to 0.2% (PESI, Bova), and 3.0% (Bova) to 5.7% (PESI) in the highest risk groups, respectively. All four scores produced statistically significant discrimination between different risk strata. However, no single scoring system was able to identify all patients with 30-day mortality. The findings of the present study suggest that PESI, sPESI, ESC, and Bova scores provide important information about 30-day mortality in Hispanic in-patients presenting with acute PE. However, additional clinical information could further improve predictability that is not provided by a single scoring system.
期刊介绍:
A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days