Magdalena Piringer , Lotte Stockhammer , Lukas Vogl , David Weinzierl , Paul Zebrowski , Mario Waser
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Enantioselective α-heterofunctionalization reactions of catalytically generated C1-Lewis base enolates
Chiral Lewis base (LB) organocatalysis has emerged as a powerful covalent catalysis concept which allows for highly selective asymmetric C–C and C-heteroatom bond formations. Considering significant recent progress in the development of strategies to access α-heterofunctionalized carboxylic acid derivatives under chiral LB catalysis, we wish to summarize the most significant concepts and advances in this field within this mini review now.
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