Argjend Shala, Afrim Blyta, N. Shala, D. Boshnjaku, P. Ibrahimi, F. Jashari
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引用次数: 0
摘要
背景。中风后早期癫痫发作(ES)在老年人群中很普遍,是获得性癫痫发作中最常见的类型。本研究旨在确定 ES 的发病率,并调查与各种临床和放射学因素的潜在关联。材料和方法。对 260 名脑卒中患者(平均年龄为 72±13.2,女性占 48.5%)进行了前瞻性登记和随访。收集并分析了基线人口统计学数据、临床数据、卒中亚型、ES发生率、美国国立卫生研究院卒中量表(NIHSS)评分和阿尔伯塔省卒中计划早期CT评分(ASPECT)。结果11.6%的缺血性脑卒中患者观察到ES,而出血性脑卒中患者仅为7.1%。后循环卒中患者(18.5% 对 7.1%,P=0.008)和 NIHSS >15 的患者(19.4% 对 8.4%,P=0.04)ES 发生率更高。在对血管风险因素和 NIHSS 进行调整的逻辑回归分析中,后循环卒中仍与 ES 显著相关,几率比为 3.14(95% CI 1.20 至 7.73,P=0.012)。结论本研究显示,脑卒中后ES在后循环病变患者中更为常见。这些发现强调有必要进一步研究可能影响 ES 发生的其他因素及其对卒中管理和患者预后的影响。
Posterior circulation lesions are more frequently associated with early seizures after a stroke
Background. Early seizures (ES) following stroke are prevalent among the elderly population, representing the most common type of acquired seizures. This study aimed to determine the incidence of ES and investigate potential associations with various clinical and radiological factors. Materials and Methods. 260 stroke patients (mean age 72±13.2, 48.5% females) were prospectively enrolled and followed. Baseline demographic data, clinical data, stroke subtype, ES occurrence, National Institutes of Health Stroke Scale (NIHSS) scores, and Alberta Stroke Program Early CT Score (ASPECT) were collected and analyzed. Results. ES was observed in 11.6% of patients with ischemic stroke compared to 7.1% among patients with hemorrhagic stroke. ES occurred more frequently in those with posterior circulation stroke (18.5% vs. 7.1%, P=0.008) and those with NIHSS >15 (19.4% vs. 8.4%, P=0.04). In a logistic regression analysis that adjusted for vascular risk factors and NIHSS, posterior circulation stroke remained significantly associated with ES, with an odds ratio of 3.14 (95% CI 1.20 to 7.73, P=0.012). Conclusions. This study revealed that ES following stroke is more common in patients with posterior circulation lesions. These findings emphasize the need for further investigation into additional factors that may influence ES occurrence and its impact on stroke management and patient outcomes.