Direzione Scientifica, S. Squatrito, Catania Direttore, Responsabile Stefano Melloni, Maurizio Sabrina Scilletta, D. Marco, Nicoletta Miano, Agnese Filippello, S. D. Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, F. di, Giacomo Barbagallo, Giosiana Bosco, Roberto Scicali, S. Piro, Francesco Purrello, A. Pino
{"title":"糖尿病肾病 (DKD) 的最新进展：关注非白蛋白尿型 DKD 和心血管风险","authors":"Direzione Scientifica, S. Squatrito, Catania Direttore, Responsabile Stefano Melloni, Maurizio Sabrina Scilletta, D. Marco, Nicoletta Miano, Agnese Filippello, S. D. Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, F. di, Giacomo Barbagallo, Giosiana Bosco, Roberto Scicali, S. Piro, Francesco Purrello, A. Pino","doi":"10.30682/ildia2304a","DOIUrl":null,"url":null,"abstract":"The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.","PeriodicalId":119243,"journal":{"name":"Il Diabete","volume":" 7","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":"{\"title\":\"Update sulla malattia renale diabetica (DKD): focus sulla DKD non albuminurica e il rischio cardiovascolare\",\"authors\":\"Direzione Scientifica, S. Squatrito, Catania Direttore, Responsabile Stefano Melloni, Maurizio Sabrina Scilletta, D. Marco, Nicoletta Miano, Agnese Filippello, S. D. Mauro, Alessandra Scamporrino, Marco Musmeci, Giuseppe Coppolino, F. di, Giacomo Barbagallo, Giosiana Bosco, Roberto Scicali, S. Piro, Francesco Purrello, A. Pino\",\"doi\":\"10.30682/ildia2304a\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.\",\"PeriodicalId\":119243,\"journal\":{\"name\":\"Il Diabete\",\"volume\":\" 7\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"3\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Il Diabete\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30682/ildia2304a\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Il Diabete","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30682/ildia2304a","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Update sulla malattia renale diabetica (DKD): focus sulla DKD non albuminurica e il rischio cardiovascolare
The classic description of diabetic kidney disease (DKD) involves progressive stages of glomerular hyperfiltration, microalbuminuria, and a decline in the estimated glomerular filtration rate (eGFR). However, large studies have revealed that eGFR decline may also occur independently from development of albuminuria. This concept led to the identification of a new phenotype: non-albuminuric DKD, whose pathogenesis is still unknown and data in literature are still controversial. This review is focused on cardiovascular risk profile and therapeutical implication of this new DKD phenotype.
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