转移性胰腺癌：我们在哪里？

IF 3.1 Q2 ONCOLOGY

Oncology Reviews Pub Date : 2024-01-18 DOI:10.3389/or.2023.11364

Abraham Hernández-Blanquisett, Valeria Quintero-Carreño, M. C. Martínez-Ávila, María Porto, María Carolina Manzur-Barbur, Emiro Buendía

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引用次数: 0

摘要

胰腺癌是全球致死率最高的肿瘤之一，具有侵袭性，预后较差。胰腺癌的总生存率很低。大多数患者在晚期会出现非特异性症状，这通常会导致晚期诊断，此时已无法选择根治性手术。转移性胰腺癌的治疗包括全身治疗，在某些情况下也包括放射治疗，以及最近出现的分子靶向疗法，这些疗法可对癌症控制和改善生活质量产生积极影响。本综述根据最新文献概述了胰腺癌的分子状况，以及转移性胰腺癌患者目前的治疗方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Metastatic Pancreatic Cancer: Where Are We?

Pancreatic cancer is one of the most lethal neoplasms worldwide; it is aggressive in nature and has a poor prognosis. The overall survival rate for pancreatic cancer is low. Most patients present non-specific symptoms in the advanced stages, which generally leads to late diagnosis, at which point there is no option for curative surgery. The treatment of metastatic pancreatic cancer includes systemic therapy, in some cases radiotherapy, and more recently, molecular targeted therapies, which can positively impact cancer control and improve quality of life. This review provides an overview of the molecular landscape of pancreatic cancer based on the most recent literature, as well as current treatment options for patients with metastatic pancreatic cancer.

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来源期刊

Oncology Reviews ONCOLOGY-

CiteScore

6.30

自引率

0.00%

发文量

审稿时长

9 weeks

期刊介绍： Oncology Reviews is a quarterly peer-reviewed, international journal that publishes authoritative state-of-the-art reviews on preclinical and clinical aspects of oncology. The journal will provide up-to-date information on the latest achievements in different fields of oncology for both practising clinicians and basic researchers. Oncology Reviews aims at being international in scope and readership, as reflected also by its Editorial Board, gathering the world leading experts in both pre-clinical research and everyday clinical practice. The journal is open for publication of supplements, monothematic issues and for publishing abstracts of scientific meetings; conditions can be obtained from the Editor-in-Chief or the publisher.