计算哺乳动物红细胞表面积的简化方法

IF 2.3 Q3 BIOCHEMICAL RESEARCH METHODS
I. Udroiu
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引用次数: 0

摘要

对于动物学家和兽医来说,了解红细胞的几何数量对一些生理研究非常有用。虽然直径和体积(MCV)很容易通过观察血涂片和全血细胞计数获得,但厚度和表面积却很难测量。卡西尼椭圆方程给出了红细胞几何形状的精确描述,但由此得出的公式非常复杂,包括椭圆积分。本文提出了三种近似红细胞的固体模型:球体、圆柱体和带凹帽的球体。通过这些模型得到的体积和表面积与有效测量值进行了比较。带凹帽的球形红细胞的近似度最高,可用作确定红细胞表面积的简单模型。利用这一模型,我们提出了一种简单的方法,只需知道直径和 MCV 即可估算表面积。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Simplified Method for Calculating Surface Area of Mammalian Erythrocytes
Knowledge of the geometric quantities of the erythrocyte is useful in several physiological studies, both for zoologists and veterinarians. While the diameter and volume (MCV) are easily obtained from observations of blood smears and complete blood count, respectively, the thickness and surface area are instead much more difficult to measure. The precise description of the erythrocyte geometry is given by the equation of the oval of Cassini, but the formulas deriving from it are very complex, comprising elliptic integrals. In this article, three solids are proposed as models approximating the erythrocyte: sphere, cylinder and a spheroid with concave caps. The volumes and surface areas obtained with these models are compared to those effectively measured. The spheroid with concave caps gives the best approximation and can be used as a simple model to determine the erythrocyte surface area. With this model, a simple method that allows one to estimate the surface area by knowing only the diameter and MCV is proposed.
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来源期刊
Methods and Protocols
Methods and Protocols Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (miscellaneous)
CiteScore
3.60
自引率
0.00%
发文量
85
审稿时长
8 weeks
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